| Literature DB >> 29316440 |
Christopher K Patil1, Vladimir Denic2.
Abstract
In a recent issue of Nature, Bohnert and Kenyon (2017) describe a signaling pathway that prevents transgenerational inheritance of cytoplasmic protein aggregates. Fertilizing sperm trigger aggregate clearance in the ovum by a microautophagy-like effector mechanism mediated by inter-organelle communication between lysosomes and mitochondria.Entities:
Mesh：
Year: 2018 PMID： 29316440 PMCID： PMC9215319 DOI： 10.1016/j.devcel.2017.12.016
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 13.417