Qiukui Hao1, Xiaoyi Hu1, Linlin Xie1, Jing Chen1, Jiaojiao Jiang2, Birong Dong1, Ming Yang1. 1. The Center of Gerontology and Geriatrics, West China Hospital of Sichuan University, Chengdu, China. 2. The Center of Rehabilitation, West China Hospital of Sichuan University, Chengdu, China.
Abstract
OBJECTIVE: To estimate the prevalence and factors associated with sarcopenia in a sample of older inpatients. METHODS: A cross-sectional study was conducted in three acute geriatric wards in 2012. Sarcopenia was defined according to the criteria of the Asian Working Group for Sarcopenia. RESULTS: We included 407 patients aged 81.0 ± 8.0 years. The prevalence of sarcopenia was 31% in the whole study population. Multiple logistic regression showed that being a female (odds ratio (OR) 4.75, 95% confidence interval (CI) 2.45-9.20), smoking (OR 2.94, 95% CI 1.26-6.69), cognitive impairment (OR 2.08, 95% CI 1.10-3.95), polypharmacy (OR 2.36, 95% CI 1.28-4.34) and body mass index (OR 0.75, 95% CI 0.68-0.83) were independently associated with sarcopenia. CONCLUSION: Sarcopenia was highly prevalent in older inpatients. In addition to factors previously reported to be associated with sarcopenia, we found that polypharmacy was associated with sarcopenia. As the direction of causality remains uncertain, these relationships deserve further study.
OBJECTIVE: To estimate the prevalence and factors associated with sarcopenia in a sample of older inpatients. METHODS: A cross-sectional study was conducted in three acute geriatric wards in 2012. Sarcopenia was defined according to the criteria of the Asian Working Group for Sarcopenia. RESULTS: We included 407 patients aged 81.0 ± 8.0 years. The prevalence of sarcopenia was 31% in the whole study population. Multiple logistic regression showed that being a female (odds ratio (OR) 4.75, 95% confidence interval (CI) 2.45-9.20), smoking (OR 2.94, 95% CI 1.26-6.69), cognitive impairment (OR 2.08, 95% CI 1.10-3.95), polypharmacy (OR 2.36, 95% CI 1.28-4.34) and body mass index (OR 0.75, 95% CI 0.68-0.83) were independently associated with sarcopenia. CONCLUSION:Sarcopenia was highly prevalent in older inpatients. In addition to factors previously reported to be associated with sarcopenia, we found that polypharmacy was associated with sarcopenia. As the direction of causality remains uncertain, these relationships deserve further study.