Literature DB >> 2931447

Alterations of functional subsets of T helper and T suppressor cell populations in acquired immunodeficiency syndrome (AIDS) and chronic unexplained lymphadenopathy.

J K Nicholson, J S McDougal, T J Spira.   

Abstract

We have studied the distribution of Leu8 and Ia on T cells of the helper (T4) and suppressor (T8) phenotype in homosexual men with chronic unexplained lymphadenopathy, homosexual men with the acquired immunodeficiency syndrome (AIDS), and homosexual and heterosexual controls. Decreased numbers of helper T cells in lymphadenopathy patients are due to a decrease in the T4:Leu8+ subset, whereas in AIDS patients, both the T4:Leu8+ and the T4:Leu8- subsets were decreased.

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Year:  1985        PMID： 2931447     DOI： 10.1007/BF00929462

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  14 in total

1.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

2.  Studies of cellular immunity in male homosexuals in London.

Authors:  A J Pinching; T J McManus; D J Jeffries; O Moshtael; M Donaghy; J M Parkin; P E Munday; J R Harris
Journal:  Lancet       Date:  1983-07-16       Impact factor: 79.321

3.  Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage.

Authors:  N Mohagheghpour; C J Benike; G Kansas; C Bieber; E G Engleman
Journal:  J Clin Invest       Date:  1983-12       Impact factor: 14.808

4.  T-lymphocyte subpopulations in homosexual men.

Authors:  H Kornfeld; R A Vande Stouwe; M Lange; M M Reddy; M H Grieco
Journal:  N Engl J Med       Date:  1982-09-16       Impact factor: 91.245

5.  Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

Authors:  E L Reinherz; C Morimoto; K A Fitzgerald; R E Hussey; J F Daley; S F Schlossman
Journal:  J Immunol       Date:  1982-01       Impact factor: 5.422

6.  Ia determinants on human T-cell subsets defined by monoclonal antibody. Activation stimuli required for expression.

Authors:  E L Reinherz; P C Kung; J M Pesando; J Ritz; G Goldstein; S F Schlossman
Journal:  J Exp Med       Date:  1979-12-01       Impact factor: 14.307

7.  Seroepidemiological studies of human T-lymphotropic retrovirus type III in acquired immunodeficiency syndrome.

Authors:  B Safai; M G Sarngadharan; J E Groopman; K Arnett; M Popovic; A Sliski; J Schüpbach; R C Gallo
Journal:  Lancet       Date:  1984-06-30       Impact factor: 79.321

8.  Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency.

Authors:  M S Gottlieb; R Schroff; H M Schanker; J D Weisman; P T Fan; R A Wolf; A Saxon
Journal:  N Engl J Med       Date:  1981-12-10       Impact factor: 91.245

9.  Dissection of immunoregulatory subpopulations of T lymphocytes within the helper and suppressor sublineages in man.

Authors:  P A Gatenby; G S Kansas; C Y Xian; R L Evans; E G Engleman
Journal:  J Immunol       Date:  1982-11       Impact factor: 5.422

10.  Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.

Authors:  R C Gallo; S Z Salahuddin; M Popovic; G M Shearer; M Kaplan; B F Haynes; T J Palker; R Redfield; J Oleske; B Safai
Journal:  Science       Date:  1984-05-04       Impact factor: 47.728
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  7 in total

1.  Preferential loss of Leu 8-, CD45R, HLA-DR+ CD8 cell subsets during in vitro culture of mononuclear cells from human immunodeficiency virus type I (HIV)-seropositive former blood donors.

Authors:  H E Prince; C D Czaplicki
Journal:  J Clin Immunol       Date:  1989-09       Impact factor: 8.317

2.  PolyI.polyC12U-mediated inhibition of loss of alloantigen responsiveness viral replication in human CD4+ T cell clones exposed to human immunodeficiency virus in vitro.

Authors:  J Laurence; J Kulkosky; S M Friedman; D N Posnett; P O Ts'o
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

3.  Assessment of CD8 T cell immune activation markers to monitor response to antiretroviral therapy among HIV-1 infected patients in Côte d'Ivoire.

Authors:  P Ondoa; S Koblavi-Dème; M-Y Borget; M L Nolan; J N Nkengasong; L Kestens
Journal:  Clin Exp Immunol       Date:  2005-04       Impact factor: 4.330

4.  Selective alterations in immunoregulatory lymphocyte subsets in early HIV (human T-lymphotropic virus type III/lymphadenopathy-associated virus) infection.

Authors:  J V Giorgi; P G Nishanian; I Schmid; L E Hultin; H L Cheng; R Detels
Journal:  J Clin Immunol       Date:  1987-03       Impact factor: 8.317

5.  The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value.

Authors:  M Levacher; F Hulstaert; S Tallet; S Ullery; J J Pocidalo; B A Bach
Journal:  Clin Exp Immunol       Date:  1992-12       Impact factor: 4.330

6.  Deterioration in immunologic status of human immunodeficiency virus (HIV)-infected homosexual men with lymphadenopathy: prognostic implications.

Authors:  T J Spira; J E Kaplan; R C Holman; L H Bozeman; J K Nicholson; D B Fishbein
Journal:  J Clin Immunol       Date:  1989-03       Impact factor: 8.317

7.  Human immunodeficiency virus-associated vitiligo: expression of autoimmunity with immunodeficiency?

Authors:  M Duvic; R Rapini; W K Hoots; P W Mansell
Journal:  J Am Acad Dermatol       Date:  1987-10       Impact factor: 11.527
  7 in total

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