Literature DB >> 29313529

Bad germs are trapped.

Liman Zhang1, Hao Wu1.   

Abstract

Activation of the NAIP/NLRC4 inflammasomes initiates inflammatory responses against bacterial invasion. Two recent reports described the cryo-EM structure of the flagellin/NAIP5 complex, providing important insights into the mechanism of bacterial sensing by innate immunity.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29313529      PMCID： PMC5799821          DOI： 10.1038/cr.2018.5

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  8 in total

1.  Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome.

Authors:  Valeria M Reyes Ruiz; Jasmine Ramirez; Nawar Naseer; Nicole M Palacio; Ingharan J Siddarthan; Brian M Yan; Mark A Boyer; Daniel A Pensinger; John-Demian Sauer; Sunny Shin
Journal:  Proc Natl Acad Sci U S A       Date:  2017-11-27       Impact factor: 11.205

2.  The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Authors:  Yue Zhao; Jieling Yang; Jianjin Shi; Yi-Nan Gong; Qiuhe Lu; Hao Xu; Liping Liu; Feng Shao
Journal:  Nature       Date:  2011-09-14       Impact factor: 49.962

3.  Crystal structure of NLRC4 reveals its autoinhibition mechanism.

Authors:  Zehan Hu; Chuangye Yan; Peiyuan Liu; Zhiwei Huang; Rui Ma; Chenlu Zhang; Ruiyong Wang; Yueteng Zhang; Fabio Martinon; Di Miao; Haiteng Deng; Jiawei Wang; Junbiao Chang; Jijie Chai
Journal:  Science       Date:  2013-06-13       Impact factor: 47.728

4.  Structural and biochemical basis for induced self-propagation of NLRC4.

Authors:  Zehan Hu; Qiang Zhou; Chenlu Zhang; Shilong Fan; Wei Cheng; Yue Zhao; Feng Shao; Hong-Wei Wang; Sen-Fang Sui; Jijie Chai
Journal:  Science       Date:  2015-10-08       Impact factor: 47.728

5.  Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.

Authors:  Liman Zhang; Shuobing Chen; Jianbin Ruan; Jiayi Wu; Alexander B Tong; Qian Yin; Yang Li; Liron David; Alvin Lu; Wei Li Wang; Carolyn Marks; Qi Ouyang; Xinzheng Zhang; Youdong Mao; Hao Wu
Journal:  Science       Date:  2015-10-08       Impact factor: 47.728

6.  The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.

Authors:  Jeannette L Tenthorey; Nicole Haloupek; José Ramón López-Blanco; Patricia Grob; Elise Adamson; Ella Hartenian; Nicholas A Lind; Natasha M Bourgeois; Pablo Chacón; Eva Nogales; Russell E Vance
Journal:  Science       Date:  2017-11-17       Impact factor: 47.728

7.  Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.

Authors:  Eric M Kofoed; Russell E Vance
Journal:  Nature       Date:  2011-08-28       Impact factor: 49.962

8.  Structural basis for specific flagellin recognition by the NLR protein NAIP5.

Authors:  Xinru Yang; Fan Yang; Weiguang Wang; Guangzhong Lin; Zehan Hu; Zhifu Han; Yijun Qi; Liman Zhang; Jiawei Wang; Sen-Fang Sui; Jijie Chai
Journal:  Cell Res       Date:  2017-11-28       Impact factor: 25.617
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.