Literature DB >> 29313483

Low Prevalence of Tuberculin Skin Test Boosting among Community Residents in Uganda.

Juliet N Sekandi1,2, Sarah Zalwango3,4, Allan K Nkwata2, Leonardo Martinez2,1, Robert Kakaire2,1, Jane N Mutanga2, Christopher C Whalen2,1, Noah Kiwanuka4.   

Abstract

Boosted tuberculin skin test (TST) reactions can be misclassified as new latent tuberculosis (TB) infection. To our knowledge, no study has evaluated the prevalence of TST boosting in a population-based sample in high TB burden settings. We determined the prevalence of TST boosting among urban residents in Uganda. We evaluated 99 participants with initial TST < 5 mm and repeated a skin test after 2 weeks. We found that only 2% had boosted TST reactions suggesting that most TST conversions could represent new TB infections in this high-burden setting.

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Year:  2018        PMID： 29313483      PMCID： PMC5929205          DOI： 10.4269/ajtmh.17-0591

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  11 in total

1.  A 19-year follow-up of tuberculin reactors. Assessment of skin test reactivity and in vitro lymphocyte responses.

Authors:  D V Havlir; F van der Kuyp; E Duffy; R Marshall; D Hom; J J Ellner
Journal:  Chest       Date:  1991-05       Impact factor: 9.410

Review 2.  Recent advances in testing for latent TB.

Authors:  Neil W Schluger; Joseph Burzynski
Journal:  Chest       Date:  2010-12       Impact factor: 9.410

3.  Diagnosis of latent tuberculosis infection: measure for measure.

Authors:  Christopher C Whalen
Journal:  JAMA       Date:  2005-06-08       Impact factor: 56.272

Review 4.  Interpretation of repeated tuberculin tests. Boosting, conversion, and reversion.

Authors:  D Menzies
Journal:  Am J Respir Crit Care Med       Date:  1999-01       Impact factor: 21.405

5.  Two-step tuberculin skin testing in HIV-infected persons in Uganda.

Authors:  M T Hecker; J L Johnson; C C Whalen; S Nyole; R D Mugerwa; J J Ellner
Journal:  Am J Respir Crit Care Med       Date:  1997-01       Impact factor: 21.405

6.  Within-subject variability and boosting of T-cell interferon-gamma responses after tuberculin skin testing.

Authors:  Richard N van Zyl-Smit; Madhukar Pai; Kwaku Peprah; Richard Meldau; Jackie Kieck; June Juritz; Motasim Badri; Alimuddin Zumla; Leonardo A Sechi; Eric D Bateman; Keertan Dheda
Journal:  Am J Respir Crit Care Med       Date:  2009-04-02       Impact factor: 21.405

7.  Two-step tuberculin skin test and booster phenomenon prevalence among Brazilian medical students.

Authors:  E G Teixeira; A Kritski; A Ruffino-Netto; R Steffen; J R Lapa E Silva; M Belo; R R Luiz; D Menzies; A Trajman
Journal:  Int J Tuberc Lung Dis       Date:  2008-12       Impact factor: 2.373

8.  Interpretation of repeat tuberculin skin testing in international adoptees: conversions or boosting.

Authors:  Anna M Mandalakas; H Lester Kirchner; Xaiobei Zhu; Kee Thai Yeo; Jeffrey R Starke
Journal:  Pediatr Infect Dis J       Date:  2008-10       Impact factor: 2.129

9.  The presence of a booster phenomenon among contacts of active pulmonary tuberculosis cases: a retrospective cohort.

Authors:  Cristiane G Salles; Antonio Ruffino-Netto; Jose R Lapa-e-Silva; Afranio L Kritski; Michelle Cailleaux-Cesar; Fernanda C Queiroz-Mello; Marcus B Conde
Journal:  BMC Public Health       Date:  2007-03-19       Impact factor: 3.295

Review 10.  Within-subject variability of interferon-g assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review.

Authors:  Richard N van Zyl-Smit; Alice Zwerling; Keertan Dheda; Madhukar Pai
Journal:  PLoS One       Date:  2009-12-30       Impact factor: 3.240
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  2 in total

1.  Performance of the QuantiFERON®-TB Gold In-Tube assay in tuberculin skin test converters: a prospective cohort study.

Authors:  M E Castellanos; S Kirimunda; L Martinez; T Quach; H Woldu; R Kakaire; A Handel; S Zalwango; N Kiwanuka; C C Whalen
Journal:  Int J Tuberc Lung Dis       Date:  2018-09-01       Impact factor: 2.373

2.  Defining an intermediate category of tuberculin skin test: A mixture model analysis of two high-risk populations from Kampala, Uganda.

Authors:  Henok G Woldu; Sarah Zalwango; Leonardo Martinez; María Eugenia Castellanos; Robert Kakaire; Juliet N Sekandi; Noah Kiwanuka; Christopher C Whalen
Journal:  PLoS One       Date:  2021-01-22       Impact factor: 3.240
  2 in total

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