| Literature DB >> 29313470 |
Cintya O Souza1, Marcelo A C S Vieira2,3,4, Francisca M A Batista5, Kelsen D Eulálio3,4, Jéssica M M Neves6, Laís C Sá7, Leni C R Monteiro1, Walfrido S Almeida-Neto4, Raimunda S S Azevedo8, Dorcas L Costa9, Ana C R Cruz8.
Abstract
In countries where poliomyelitis has been eradicated, Guillain-Barré syndrome (GBS) is the leading cause of acute flaccid paralysis. The range of infections that precede GBS in Brazil is unknown. Campylobacter jejuni infection is the most frequent trigger of GBS worldwide. Given the lack of systematic surveillance of diarrheal diseases, particularly in adults, the incidence of enteritis caused by C. jejuni in developing countries is unknown. From 2014 to 2016, pretreatment serum samples from 63 GBS patients were tested by immunoglobulin M (IgM) enzyme-linked immunosorbent assay for C. jejuni. Campylobacter jejuni IgM antibodies were detected in 17% (11/63) of the samples. There was no association between serological positivity (IgM) for C. jejuni and the occurrence of diarrhea among the investigated cases (P = 0.36). Hygiene measures, basic sanitation, and precautions during handling and preparation of food of animal origin may help prevent acute flaccid paralysis.Entities:
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Year: 2018 PMID： 29313470 PMCID： PMC5929210 DOI： 10.4269/ajtmh.17-0666
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345