Literature DB >> 29311223

Genomic Analyses and Precision Oncology in Gastroesophageal Cancer: Forwards or Backwards?

Raghav Sundar1, Patrick Tan2,3,4,5.   

Abstract

<b/> Gastroesophageal adenocarcinoma (GEA) comprises a myriad of distinct subtypes with significant interpatient, intrapatient, and intratumor heterogeneity. Strategies for tackling molecular heterogeneity will be essential for the success of GEA precision oncology-in this regard, blood-based "liquid biopsies" may provide broader views of the real-time genomic landscape of this disease, identifying actionable biomarkers and monitoring therapy resistance. Cancer Discov; 8(1); 14-6. ©2018 AACRSee related article by Pectasides et al., p. 37See related article by Janjigian et al., p. 49. ©2018 American Association for Cancer Research.

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Year:  2018        PMID： 29311223     DOI： 10.1158/2159-8290.CD-17-1295

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  6 in total

1.  Reply to: Letter to editor on the article "Choice of PD-L1 immunohistochemistry assay influences clinical eligibility for gastric cancer immunotherapy".

Authors:  Joe Yeong; Chong Boon Teo; Ryan Yong Kiat Tay; Benjamin Kye Jyn Tan; Yiong Huak Chan; Elizabeth C Smyth; Raghav Sundar
Journal:  Gastric Cancer       Date:  2022-09-24       Impact factor: 7.701

2.  Case Report: Complete Remission of a Patient With Metastatic Gastric Cancer Treated With Nivolumab Combined With Chemotherapy After Palliative Surgery.

Authors:  Peilin Dai; Xi Rao; Xi Zhang; Enming Qiu; Gang Wu; Yu Lin; Sitong Li; Zhou Li; Zhai Cai; Shuai Han
Journal:  Front Immunol       Date:  2022-06-29       Impact factor: 8.786

3.  Comparative Molecular Analyses of Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, and Gastric Adenocarcinoma.

Authors:  Mohamed E Salem; Alberto Puccini; Joanne Xiu; Derek Raghavan; Heinz-Josef Lenz; W Michael Korn; Anthony F Shields; Philip A Philip; John L Marshall; Richard M Goldberg
Journal:  Oncologist       Date:  2018-06-04

4.  Profiling of gastric cancer cell-surface markers to achieve tumour-normal discrimination.

Authors:  Judith Toh; Michal Marek Hoppe; Teena Thakur; Henry Yang; Kar Tong Tan; Brendan Pang; Sharmaine Ho; Rony Roy; Khek Yu Ho; Khay Guan Yeoh; Patrick Tan; Raghav Sundar; Anand Jeyasekharan
Journal:  BMJ Open Gastroenterol       Date:  2020-08

5.  Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination.

Authors:  Raghav Sundar; Drolaiz Hw Liu; Gordon Ga Hutchins; Hayley L Slaney; Arnaldo Ns Silva; Jan Oosting; Jeremy D Hayden; Lindsay C Hewitt; Cedric Cy Ng; Amrita Mangalvedhekar; Sarah B Ng; Iain Bh Tan; Patrick Tan; Heike I Grabsch
Journal:  Gut       Date:  2020-11-23       Impact factor: 23.059

6.  Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial.

Authors:  Raghav Sundar; Nesaretnam Barr Kumarakulasinghe; Yiong Huak Chan; Kazuhiro Yoshida; Takaki Yoshikawa; Yohei Miyagi; Yasushi Rino; Munetaka Masuda; Jia Guan; Junichi Sakamoto; Shiro Tanaka; Angie Lay-Keng Tan; Michal Marek Hoppe; Anand D Jeyasekharan; Cedric Chuan Young Ng; Mark De Simone; Heike I Grabsch; Jeeyun Lee; Takashi Oshima; Akira Tsuburaya; Patrick Tan
Journal:  Gut       Date:  2021-05-12       Impact factor: 23.059
  6 in total

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