Tomoyasu Tachibana1, Yorihisa Orita2, Takuma Makino1, Yasutoshi Komatsubara1, Yuko Matsuyama1, Yuto Naoi1, Michihiro Nakada3, Yasuharu Sato4, Kazunori Nishizaki5. 1. a Department of Otolaryngology , Himeji Red Cross Hospital , Himeji City , Japan. 2. b Department of Otolaryngology Head and Neck Surgery , Kumamoto University Graduate School of Medicine , Kumamoto City , Japan. 3. c Otolaryngology , Nakada ENT Clinic , Himeji City , Japan. 4. d Pathology, Dentistry and Pharmaceutical Sciences , Okayama University Graduate School of Medicine , Okayama , Japan. 5. e Department of Otolaryngology Head and Neck Surgery , Okayama University Graduate School of Medicine , Okayama , Japan.
Abstract
OBJECTIVES: Croup, or laryngotracheobronchitis, is a common disease in childhood. On the other hand, to our knowledge, there are only 14 cases in six English literatures describing adult croup (AC). The clinical features of AC have not been well known. METHODS: We conducted a retrospective analysis of medical records of 18 patients with AC during the period from 2008 to 2016. RESULTS: None of the 18 patients required an urgent airway intervention. Univariate analysis indicated that the duration of symptoms was significantly longer in patients with cough (p < .01) and younger patients (age < 60, p = .037). The duration of subglottic edema was significantly longer in female (p = .035), patients with high levels of CRP (≥1 mg/dL, p = .049), and patients with cough symptom (p = .035). CONCLUSIONS: Female, young age (<60 years), the symptom of cough, and high levels of CRP should be recognized as signs of prolonged AC. It is important to confirm the diagnosis of AC by laryngoscopic examination, which also help to avoid airway intervention.
OBJECTIVES: Croup, or laryngotracheobronchitis, is a common disease in childhood. On the other hand, to our knowledge, there are only 14 cases in six English literatures describing adult croup (AC). The clinical features of AC have not been well known. METHODS: We conducted a retrospective analysis of medical records of 18 patients with AC during the period from 2008 to 2016. RESULTS: None of the 18 patients required an urgent airway intervention. Univariate analysis indicated that the duration of symptoms was significantly longer in patients with cough (p < .01) and younger patients (age < 60, p = .037). The duration of subglottic edema was significantly longer in female (p = .035), patients with high levels of CRP (≥1 mg/dL, p = .049), and patients with cough symptom (p = .035). CONCLUSIONS: Female, young age (<60 years), the symptom of cough, and high levels of CRP should be recognized as signs of prolonged AC. It is important to confirm the diagnosis of AC by laryngoscopic examination, which also help to avoid airway intervention.
Entities:
Keywords:
Adult croup; airway intervention; early diagnosis; prognostic factors; stridor