Taku Sakamoto1, Takeshi Nakajima1, Takahisa Matsuda2, Yoshitaka Murakami3, Hideki Ishikawa4, Kenshi Yao5, Yutaka Saito1. 1. Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan. 2. Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan; Division of Screening Technology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan. 3. Department of Medical Statistics, Toho University, Tokyo, Japan. 4. Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. 5. Department of Endoscopy Fukuoka University Chikushi Hospital, Fukuoka, Japan.
Abstract
BACKGROUND AND AIMS: Magnifying narrow-band imaging (mag-NBI) and magnifying chromoendoscopy using crystal violet staining for pit pattern analysis (pit pattern) is highly accurate for diagnosing invasion depth of superficial colorectal neoplasms. However, NBI and pit pattern have not been compared. METHODS: We conducted an online survey of endoscopists interested in image-enhanced endoscopy. Still images using white light, mag-NBI, and pit pattern were collected from lesions diagnosed at the National Cancer Center Hospital (NCCH), Tokyo, Japan. Sixty endoscopists from outside NCCH who typically use magnifying endoscopy were recruited for this survey. We assessed the diagnostic accuracy using receiver operating characteristic (ROC) analysis based on a calculation of the area under the ROC curve. RESULTS: One hundred early colorectal neoplasms were selected for this survey. Histopathology revealed that, although 67 of the lesions had high-grade dysplasia or carcinoma with superficial submucosal (SM-s) invasion, the other 33 lesions had a carcinoma with deep submucosal invasion (SM-d). Comparing the area under the ROC curve from mag-NBI with that of pit pattern, the latter showed significantly higher diagnostic accuracy for depth invasion (0.83 [95% CI, 0.81-0.85] for mag-NBI, 0.88 [95% CI, 0.85-0.89] for pit pattern, P = .013). CONCLUSIONS: Pit pattern should be the first choice for diagnosing invasion depth as the most reliable modality rather than mag-NBI.
BACKGROUND AND AIMS: Magnifying narrow-band imaging (mag-NBI) and magnifying chromoendoscopy using crystal violet staining for pit pattern analysis (pit pattern) is highly accurate for diagnosing invasion depth of superficial colorectal neoplasms. However, NBI and pit pattern have not been compared. METHODS: We conducted an online survey of endoscopists interested in image-enhanced endoscopy. Still images using white light, mag-NBI, and pit pattern were collected from lesions diagnosed at the National Cancer Center Hospital (NCCH), Tokyo, Japan. Sixty endoscopists from outside NCCH who typically use magnifying endoscopy were recruited for this survey. We assessed the diagnostic accuracy using receiver operating characteristic (ROC) analysis based on a calculation of the area under the ROC curve. RESULTS: One hundred early colorectal neoplasms were selected for this survey. Histopathology revealed that, although 67 of the lesions had high-grade dysplasia or carcinoma with superficial submucosal (SM-s) invasion, the other 33 lesions had a carcinoma with deep submucosal invasion (SM-d). Comparing the area under the ROC curve from mag-NBI with that of pit pattern, the latter showed significantly higher diagnostic accuracy for depth invasion (0.83 [95% CI, 0.81-0.85] for mag-NBI, 0.88 [95% CI, 0.85-0.89] for pit pattern, P = .013). CONCLUSIONS: Pit pattern should be the first choice for diagnosing invasion depth as the most reliable modality rather than mag-NBI.
Authors: Othman R Alharbi; Nouf S Alballa; Areej S AlRajeh; Lulwah S Alturki; Ibrahim M Alfuraih; Mouhab R Jamalaldeen; Majid A Almadi Journal: Saudi J Gastroenterol Date: 2019 Mar-Apr Impact factor: 2.485
Authors: Chan Hyuk Park; Dong-Hoon Yang; Jong Wook Kim; Jie-Hyun Kim; Ji Hyun Kim; Yang Won Min; Si Hyung Lee; Jung Ho Bae; Hyunsoo Chung; Kee Don Choi; Jun Chul Park; Hyuk Lee; Min-Seob Kwak; Bun Kim; Hyun Jung Lee; Hye Seung Lee; Miyoung Choi; Dong-Ah Park; Jong Yeul Lee; Jeong-Sik Byeon; Chan Guk Park; Joo Young Cho; Soo Teik Lee; Hoon Jai Chun Journal: Clin Endosc Date: 2020-03-30
Authors: Chan Hyuk Park; Dong-Hoon Yang; Jong Wook Kim; Jie-Hyun Kim; Ji Hyun Kim; Yang Won Min; Si Hyung Lee; Jung Ho Bae; Hyunsoo Chung; Kee Don Choi; Jun Chul Park; Hyuk Lee; Min-Seob Kwak; Bun Kim; Hyun Jung Lee; Hye Seung Lee; Miyoung Choi; Dong-Ah Park; Jong Yeul Lee; Jeong-Sik Byeon; Chan Guk Park; Joo Young Cho; Soo Teik Lee; Hoon Jai Chun Journal: Intest Res Date: 2020-10-13