Literature DB >> 29307737

Detection of carbapenemase activity in Pseudomonas aeruginosa by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS).

G Miltgen1, P Plésiat2, A Mille3, P Chatelain3, D Fournier4.   

Abstract

A new MALDI-TOF MS imipenem hydrolysis assay was developed to optimize detection of carbapenemase-producing strains of Pseudomonas aeruginosa. The method correctly discriminated carbapenemase producers (n=74) from non-producers (n=95) in 99.4% of cases, and successfully detected 100% GES-5 strains (n=5).
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Carbapenemase; Detection; MALDI-TOF MS; Pseudomonas aeruginosa

Mesh：

Substances：

Year:  2018        PMID： 29307737     DOI： 10.1016/j.mimet.2017.12.011

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  3 in total

Review 1.  Detection of carbapenemase producers by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS).

Authors:  Ioannis K Neonakis; Demetrios A Spandidos
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2019-06-28       Impact factor: 3.267

2.  Study on carbapenemase-producing bacteria by matrix-assisted laser desorption/ionization approach.

Authors:  Michał Złoch; Paweł Pomastowski; Markus Peer; Katrin Sparbier; Markus Kostrzewa; Bogusław Buszewski
Journal:  PLoS One       Date:  2021-03-18       Impact factor: 3.240

3.  Carbapenemase Producing Klebsiella pneumoniae (KPC): What Is the Best MALDI-TOF MS Detection Method.

Authors:  Lukáš Hleba; Miroslava Hlebová; Anton Kováčik; Juraj Čuboň; Juraj Medo
Journal:  Antibiotics (Basel)       Date:  2021-12-17
  3 in total

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