Klajdi Puka1,2, Mark A Ferro3, Kelly K Anderson1,2,4, Kathy N Speechley5,6,7. 1. Department of Epidemiology & Biostatistics, Western University, London, ON, Canada. 2. Children's Health Research Institute, Lawson Health Research Institute, London, ON, Canada. 3. School of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada. 4. Department of Psychiatry, Western University, London, ON, Canada. 5. Department of Epidemiology & Biostatistics, Western University, London, ON, Canada. kathy.speechley@lhsc.on.ca. 6. Children's Health Research Institute, Lawson Health Research Institute, London, ON, Canada. kathy.speechley@lhsc.on.ca. 7. Department of Paediatrics, Western University, Children's Hospital, LHSC, Room E2-602, 800 Commissioner's Road E., London, ON, N6A 5W9, Canada. kathy.speechley@lhsc.on.ca.
Abstract
PURPOSE: Epilepsy in childhood extends far beyond seizures and affects child and parental well-being. The long-term impact of childhood-onset epilepsy on parental well-being is unknown. This study assessed health-related quality of life (HRQOL) in mothers 10 years after their child's diagnosis of epilepsy. METHODS: Data come from the Health-Related Quality of Life in Children with Epilepsy Study, a multicenter prospective cohort study of children with newly diagnosed epilepsy. Mothers completed a mailed questionnaire at the 10-year follow-up, which included the Short-Form Health Survey (SF-12-v2) to evaluate the physical and mental health components of their HRQOL. Block-wise linear regressions identified child/epilepsy, maternal/family, and maternal psychosocial factors associated with mothers' HRQOL. RESULTS: A total of 159 mothers participated in this study (46% of the sample assessed at baseline). At follow-up, 69% of youth had been seizure free for the past 5 years. Mothers scored similarly to population norms (mean: 50, SD: 10) on the mental health subscale (mean: 49.5, SD: 9.3) and significantly better on the physical health subscale (mean: 53.0, SD: 7.6). Better family resources were associated with higher (better) scores on the physical health subscale (B = 0.20; 95% CI 0.03, 0.36). Better family functioning (B = 0.34; 95% CI 0.06, 0.62), fewer maternal depressive symptoms (B = 0.33; 95% CI 0.20, 0.47), and perception of less stress (B = 0.70; 95% CI 0.52, 0.88) were associated with higher (better) scores on the mental health subscale. CONCLUSION: Ten years after the diagnosis of epilepsy in children, the HRQOL of mothers was similar to reports from women in the general population. This study identified factors contributing to better maternal HRQOL and highlights the importance of family environment over epilepsy-related variables.
PURPOSE:Epilepsy in childhood extends far beyond seizures and affects child and parental well-being. The long-term impact of childhood-onset epilepsy on parental well-being is unknown. This study assessed health-related quality of life (HRQOL) in mothers 10 years after their child's diagnosis of epilepsy. METHODS: Data come from the Health-Related Quality of Life in Children with Epilepsy Study, a multicenter prospective cohort study of children with newly diagnosed epilepsy. Mothers completed a mailed questionnaire at the 10-year follow-up, which included the Short-Form Health Survey (SF-12-v2) to evaluate the physical and mental health components of their HRQOL. Block-wise linear regressions identified child/epilepsy, maternal/family, and maternal psychosocial factors associated with mothers' HRQOL. RESULTS: A total of 159 mothers participated in this study (46% of the sample assessed at baseline). At follow-up, 69% of youth had been seizure free for the past 5 years. Mothers scored similarly to population norms (mean: 50, SD: 10) on the mental health subscale (mean: 49.5, SD: 9.3) and significantly better on the physical health subscale (mean: 53.0, SD: 7.6). Better family resources were associated with higher (better) scores on the physical health subscale (B = 0.20; 95% CI 0.03, 0.36). Better family functioning (B = 0.34; 95% CI 0.06, 0.62), fewer maternal depressive symptoms (B = 0.33; 95% CI 0.20, 0.47), and perception of less stress (B = 0.70; 95% CI 0.52, 0.88) were associated with higher (better) scores on the mental health subscale. CONCLUSION: Ten years after the diagnosis of epilepsy in children, the HRQOL of mothers was similar to reports from women in the general population. This study identified factors contributing to better maternal HRQOL and highlights the importance of family environment over epilepsy-related variables.
Authors: Carolyn E Schwartz; Rita Bode; Nicholas Repucci; Janine Becker; Mirjam A G Sprangers; Peter M Fayers Journal: Qual Life Res Date: 2006-09-26 Impact factor: 4.147
Authors: Kathy N Speechley; Xuelian Sang; Simon Levin; Guang Yong Zou; Michael Eliasziw; Mary Lou Smith; Carol Camfield; Samuel Wiebe Journal: Epilepsy Behav Date: 2008-06-16 Impact factor: 2.937
Authors: Klajdi Puka; Karen Bax; Andrea Andrade; Margo Devries-Rizzo; Hema Gangam; Simon Levin; Maryam N Nouri; Asuri N Prasad; Mary Secco; Guangyong Zou; Kathy N Speechley Journal: Trials Date: 2020-11-11 Impact factor: 2.279