Yusuke S Hori1, Yuki Ebisudani2, Mizuho Aoi2, Toru Fukuhara2. 1. Department of Neurological Surgery, National Hospital Organization Okayama Medical Center, Okayama, Japan. Electronic address: ys-hori@umin.ac.jp. 2. Department of Neurological Surgery, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Abstract
BACKGROUND: Quasi-moyamoya disease is a condition that occurs in association with a specific underlying condition or disease such as atherosclerotic disease or neurofibromatosis type 1 (NF1). Pediatric cases are frequently reported, and an ischemic and bilateral presentation is more common than a hemorrhagic and unilateral presentation. CLINICAL PRESENTATION: A 39-year-old woman previously diagnosed with NF1 presented to our department with nausea and left hemiparesis. She was diagnosed with right temporal intracerebral hemorrhage by initial computed tomography. Subsequent angiography showed an occlusion of the terminal portion of the right internal carotid artery, and magnetic resonance imaging showed multiple flow voids in the right basal ganglia, suggesting quasi-moyamoya disease. The hematoma was surgically removed, and her neurological condition improved after the operation. CONCLUSIONS: This is the first reported case of quasi-moyamoya disease with a rare combination of characteristics, including an adult-onset, hemorrhagic presentation and a unilateral lesion in a patient previously diagnosed with NF1.
BACKGROUND:Quasi-moyamoya disease is a condition that occurs in association with a specific underlying condition or disease such as atherosclerotic disease or neurofibromatosis type 1 (NF1). Pediatric cases are frequently reported, and an ischemic and bilateral presentation is more common than a hemorrhagic and unilateral presentation. CLINICAL PRESENTATION: A 39-year-old woman previously diagnosed with NF1 presented to our department with nausea and left hemiparesis. She was diagnosed with right temporal intracerebral hemorrhage by initial computed tomography. Subsequent angiography showed an occlusion of the terminal portion of the right internal carotid artery, and magnetic resonance imaging showed multiple flow voids in the right basal ganglia, suggesting quasi-moyamoya disease. The hematoma was surgically removed, and her neurological condition improved after the operation. CONCLUSIONS: This is the first reported case of quasi-moyamoya disease with a rare combination of characteristics, including an adult-onset, hemorrhagic presentation and a unilateral lesion in a patient previously diagnosed with NF1.
Authors: Sciacca Francesca Luisa; Ambra Rizzo; Gloria Bedini; Fioravante Capone; Vincenzo Di Lazzaro; Sara Nava; Francesco Acerbi; Davide Sebastiano Rossi; Simona Binelli; Giuseppe Faragò; Andrea Gioppo; Marina Grisoli; Maria Grazia Bruzzone; Paolo Ferroli; Chiara Pantaleoni; Luigi Caputi; Jesus Vela Gomez; Eugenio Agostino Parati; Anna Bersano Journal: Int J Mol Sci Date: 2018-11-20 Impact factor: 5.923