| Literature DB >> 29305183 |
Lei Wang1, Hui Zhang1, Mujeeb Ur Rehman1, Khalid Mehmood2, Xiong Jiang1, Mujahid Iqbal1, Xiaole Tong1, Xing Gao1, Jiakui Li3.
Abstract
The main purpose of our study was to isolate the Lactobacillus strains from Tibetan yaks, which may have antibacterial activity. Three Lactobacillus plantarum (L. plantarum) strains named LP1, LP2, LP3 and one Pediococcus pentosaceus (P. pentosaceus) named PT2 were isolated from fecal samples of Tibetan yaks. We regarded indigenous Escherichia coli (E. coli ATCC 25922) and Staphylococcus aureus (S. aureus ATCC 25923) as indicator pathogens. The Bacteriocins derived from these isolated strains manifested high antibacterial activity against E. coli, the highest activity was observed in the case of LP1. On the other hand, PT2 had the most powerful bacteriostatic ability against S. aureus. In addition, all strains were positive for Ent A, which plays an important role in secreting pediocin-like bacteriocins and shows potential probiotic traits of bile and low PH tolerance. Overall, L. plantarum strains in present study could be employed as effective antibacterial substances and can help to remit the problem of antibiotic resistance in veterinary medicine.Entities:
Keywords: Antibacterial activity; Ent A; Lactobacillus plantarum; Tibet; Yaks
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Year: 2018 PMID： 29305183 DOI： 10.1016/j.micpath.2017.12.077
Source DB: PubMed Journal: Microb Pathog ISSN： 0882-4010 Impact factor: 3.738