Literature DB >> 2930498

Feedback regulation of S-adenosylmethionine decarboxylase synthesis.

L Persson1, A R Khomutov, R M Khomutov.   

Abstract

Treatment of Ehrlich ascites-tumour cells with 1-amino-oxy-3-aminopropane (AOAP), a potent inhibitor of ornithine decarboxylase, resulted in a marked decrease in cellular contents of putrescine and spermidine, concomitant with an arrest of cell growth. The activity of S-adenosylmethionine decarboxylase (AdoMetDC) was greatly increased in cells treated with AOAP. This increase in AdoMetDC activity was shown to be, at least partly, caused by enhanced synthesis of the enzyme, which most likely was induced by the change in cellular polyamine content.

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Year:  1989        PMID： 2930498      PMCID： PMC1135678          DOI： 10.1042/bj2570929

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  20 in total

1.  On the role of S-adenosyl-L-methionine in the biosynthesis of spermidine by rat prostate.

Authors:  A E Pegg; H G Williams-Ashman
Journal:  J Biol Chem       Date:  1969-02-25       Impact factor: 5.157

Review 2.  Polyamines.

Authors:  C W Tabor; H Tabor
Journal:  Annu Rev Biochem       Date:  1984       Impact factor: 23.643

Review 3.  Role of polyamines in the control of cell proliferation and differentiation.

Authors:  O Heby
Journal:  Differentiation       Date:  1981       Impact factor: 3.880

4.  Antibodies to ornithine decarboxylase. Immunochemical cross-reactivity.

Authors:  L Persson
Journal:  Acta Chem Scand B       Date:  1982

5.  Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells.

Authors:  P S Mamont; A M Joder-Ohlenbusch; M Nussli; J Grove
Journal:  Biochem J       Date:  1981-05-15       Impact factor: 3.857

6.  Comparison of S-adenosylmethionine decarboxylases from rat liver and muscle.

Authors:  H Pösö; A E Pegg
Journal:  Biochemistry       Date:  1982-06-22       Impact factor: 3.162

7.  Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.

Authors:  A Shirahata; A E Pegg
Journal:  J Biol Chem       Date:  1985-08-15       Impact factor: 5.157

8.  Regulation of S-adenosylmethionine decarboxylase by polyamines in Ehrlich ascites-carcinoma cells grown in culture.

Authors:  L Alhonen-Hongisto
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

9.  Investigation of structure and rate of synthesis of ornithine decarboxylase protein in mouse kidney.

Authors:  L Persson; J E Seely; A E Pegg
Journal:  Biochemistry       Date:  1984-07-31       Impact factor: 3.162

10.  Regulation of ornithine decarboxylase mRNA translation by polyamines. Studies using a cell-free system and a cell line with an amplified ornithine decarboxylase gene.

Authors:  L Persson; I Holm; O Heby
Journal:  J Biol Chem       Date:  1988-03-05       Impact factor: 5.157
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  4 in total

Review 1.  Polyamines. An overview.

Authors:  D M Morgan
Journal:  Mol Biotechnol       Date:  1999-06       Impact factor: 2.695

2.  Characterization of putrescine- and spermidine-transport systems of a rat pancreatic acinar tumoral cell line (AR4-2J).

Authors:  T G Nicolet; J L Scemama; L Pradayrol; C Seva; N Vaysse
Journal:  Biochem J       Date:  1990-08-01       Impact factor: 3.857

3.  Effect of 1-amino-oxy-3-aminopropane on polyamine metabolism and growth of L1210 cells.

Authors:  R Poulin; J A Secrist; A E Pegg
Journal:  Biochem J       Date:  1989-10-01       Impact factor: 3.857

4.  Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content.

Authors:  L M Shantz; I Holm; O A Jänne; A E Pegg
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857
  4 in total

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