Literature DB >> 29302491

An ectopic intrathyroidal thymic tissue and intrathymic parathyroid tissue in a patient with Graves disease.

Kelly O'Connor1, Hassan Alzahrani1,2, Fadi Murad1, Philip Daroca3, Emad Kandil1.   

Abstract

Ectopic intrathyroidal thymic tissue, with coinciding intrathymic parathyroid tissue, is a very rare occurrence that is most often found incidentally in adults during surgery. We report a 23-year-old female who presented with Graves disease refractory to medical treatment. Radioactive iodine uptake demonstrated increased, diffuse uptake in the region of the thyroid. The patient underwent a total thyroidectomy and right inferior parathyroidectomy which was found enlarged intraoperatively. Histopathologically, surgical specimen demonstrated characteristics of intrathyroidal thymic tissue and intrathymic parathyroid tissue. Intrathyroidal thymic tissue can be identified preoperatively on ultrasonography, but the significance of this finding is unknown.

Entities:  

Keywords:  Graves disease; Thyroidectomy; parathyroid glands; parathyroidectomy; pathology; thymus gland

Year:  2017        PMID： 29302491      PMCID： PMC5750306          DOI： 10.21037/gs.2017.08.11

Source DB:  PubMed          Journal:  Gland Surg        ISSN： 2227-684X


  9 in total

Review 1.  Thymus involution and regeneration: two sides of the same coin?

Authors:  Thomas Boehm; Jeremy B Swann
Journal:  Nat Rev Immunol       Date:  2013-09-20       Impact factor: 53.106

Review 2.  Ectopic cervical thymus: case report and review of pathogenesis and management.

Authors:  Farhan Ahsan; R Allison; J White
Journal:  J Laryngol Otol       Date:  2009-12-11       Impact factor: 1.469

Review 3.  Thymic hyperplasia in patients with Graves' disease.

Authors:  M Dalla Costa; F A Mangano; C Betterle
Journal:  J Endocrinol Invest       Date:  2014-08-23       Impact factor: 4.256

4.  Ectopic intrathyroidal thymus accompanied by intrathyroidal parathyroid as a cause of a solitary thyroid nodule in adult.

Authors:  Aeri Kim; Su Hwan Kang; Young Kyung Bae
Journal:  Int J Clin Exp Pathol       Date:  2014-08-15

5.  Aberrant cervical thymus: imaging and clinical findings in 13 children.

Authors:  I Song; S-Y Yoo; J H Kim; E Hong; H-K Yoon
Journal:  Clin Radiol       Date:  2010-10-12       Impact factor: 2.350

6.  Prevalence of ectopic intrathyroidal thymus in Japan: the Fukushima health management survey.

Authors:  Toshihiko Fukushima; Satoru Suzuki; Tetsuya Ohira; Hiroki Shimura; Sanae Midorikawa; Akira Ohtsuru; Akira Sakai; Masafumi Abe; Shunichi Yamashita; Shinichi Suzuki
Journal:  Thyroid       Date:  2015-04-07       Impact factor: 6.568

7.  Intrathyroidal ectopic thymic tissue may mimic thyroid cancer: a case report.

Authors:  Erdem Durmaz; Ebru Barsal; Mesut Parlak; Inanc Gurer; Gungor Karaguzel; Sema Akcurin; Iffet Bircan
Journal:  J Pediatr Endocrinol Metab       Date:  2012       Impact factor: 1.634

8.  Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features.

Authors:  Adalet Elcin Yildiz; Koray Ceyhan; Zeynep Sıklar; Pelin Bilir; Emin Aydın Yağmurlu; Merih Berberoğlu; Suat Fitoz
Journal:  J Ultrasound Med       Date:  2015-08-12       Impact factor: 2.153

9.  Adult perithyroid and cervical thymus-parathyroid unit: case reports of a rare entity.

Authors:  Adriana Handra-Luca
Journal:  Medicine (Baltimore)       Date:  2014-12       Impact factor: 1.889
  9 in total
  2 in total

Review 1.  Ectopic intrathyroidal thymic tissue in an adult patient: a case report and review of the literature.

Authors:  Sadegh Moradian; Sina Delazar; Farzad Yazdani; Maryam Mohammadzadeh
Journal:  J Med Case Rep       Date:  2022-05-25

2.  Intrathyroidal Thymic Tissue in an Adolescent with Graves' Disease: Case Report and Review of Current Literature.

Authors:  Liane Eng; Lisa Underland; Leslie Lam
Journal:  Case Rep Pediatr       Date:  2019-04-01
  2 in total

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