| Literature DB >> 29301918 |
Akshay Sood1, Nour A Assad2, Peter J Barnes3, Andrew Churg4, Stephen B Gordon5, Kevin S Harrod6, Hammad Irshad7, Om P Kurmi8, William J Martin9, Paula Meek10, Kevin Mortimer5, Curtis W Noonan11, Rogelio Perez-Padilla12, Kirk R Smith13, Yohannes Tesfaigzi7, Tony Ward11, John Balmes13,14.
Abstract
Exposure to household air pollution (HAP) from solid fuel combustion affects almost half of the world population. Adverse respiratory outcomes such as respiratory infections, impaired lung growth and chronic obstructive pulmonary disease have been linked to HAP exposure. Solid fuel smoke is a heterogeneous mixture of various gases and particulates. Cell culture and animal studies with controlled exposure conditions and genetic homogeneity provide important insights into HAP mechanisms. Impaired bacterial phagocytosis in exposed human alveolar macrophages possibly mediates several HAP-related health effects. Lung pathological findings in HAP-exposed individuals demonstrate greater small airways fibrosis and less emphysema compared with cigarette smokers. Field studies using questionnaires, air pollution monitoring and/or biomarkers are needed to better establish human risks. Some, but not all, studies suggest that improving cookstove efficiency or venting emissions may be associated with reduced respiratory symptoms, lung function decline in women and severe pneumonia in children. Current studies focus on fuel switching, stove technology replacements or upgrades and air filter devices. Several governments have initiated major programmes to accelerate the upgrade from solid fuels to clean fuels, particularly liquid petroleum gas, which provides research opportunities for the respiratory health community.Entities:
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Year: 2018 PMID: 29301918 PMCID: PMC7418845 DOI: 10.1183/13993003.00698-2017
Source DB: PubMed Journal: Eur Respir J ISSN: 0903-1936 Impact factor: 16.671