Literature DB >> 29299471

Outcomes of a newer-generation cementless total knee arthroplasty design in patients less than 50 years of age.

Michael A Mont1, Chukwuweike Gwam2, Jared M Newman1, Morad Chughtai1, Anton Khlopas1, Prem N Ramkumar1, Steven F Harwin3.   

Abstract

BACKGROUND: Younger patients undergoing cemented total knee arthroplasty (TKA) may be at risk for lower implant survivorship and higher revision rates due to the historical increased prevalence of aseptic loosening and instability in this cohort. The recent advances of cementless TKAs may mitigate some of these complications. However, there is a paucity of studies reporting on patients who are under 50 years who have undergone a cementless TKA. Therefore, this study evaluated: (I) implant survivorship; (II) functional outcomes and complications; and (III) radiographic outcomes in patients who were less than 50 years of age and underwent cementless TKA.
METHODS: A total of 29 patients (31 knees) younger than 50 years who underwent primary TKA at a single institution (Mount Sinai Beth Israel, New York, New York, USA) from June 2008 to May 2014 were included. Their mean follow-up was 4 years (range, 2 to 6 years). The cohort included 20 women and 9 men who had a mean age of 45 years (range, 34 to 49 years), and a mean body mass index (BMI) of 33 kg/m2 (range, 22 to 54 kg/m2). The preoperative knee diagnoses were osteoarthritis (n=24), osteonecrosis (n=5), and rheumatoid arthritis (n=2). A Kaplan-Meier analysis was used to calculate the all cause implant survivorship. Functional outcomes and all complications were recorded for each patient. Additionally, radiographic evaluation using the new Knee Society Radiographic Evaluation and Scoring System was performed.
RESULTS: The overall implant survivorship was 100%; there were no failures or revision surgeries performed as of the latest follow-up visit. At the latest follow-up, the mean Knee Society pain score was 92 points (range, 80 to 95 points) and the mean Knee Society function score was 84 points (range, 70 to 90 points). Additionally, the mean knee extension was 1 degree (range, 0 to 5 degrees) and the mean knee flexion was 125 degrees (range, 95 to 140 degrees). Furthermore, at the latest follow-up, on radiographic evaluation, there was no evidence of component loosening, subsidence, radiolucency, gap formation, or reactive changes, and there were no postoperative complications.
CONCLUSIONS: Cementless fixation of TKAs had excellent survivorship and functional and radiographic outcomes at midterm follow-up in patients younger than 50 years. Although longer follow-up is needed, these cementless TKA implants appear to provide promising results in younger patient populations.

Entities:  

Keywords:  Cementless; complications; survivorship; total knee arthroplasty (TKA); young

Year:  2017        PMID: 29299471      PMCID: PMC5750260          DOI: 10.21037/atm.2017.08.20

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  32 in total

1.  Five- to 12-year follow-up of a hydroxyapatite-coated, cementless total knee replacement in young, active patients.

Authors:  C C Tai; M J Cross
Journal:  J Bone Joint Surg Br       Date:  2006-09

2.  The influence of tibial component fixation techniques on resorption of supporting bone stock after total knee replacement.

Authors:  Desmond Y R Chong; Ulrich N Hansen; Rene van der Venne; Nico Verdonschot; Andrew A Amis
Journal:  J Biomech       Date:  2011-01-14       Impact factor: 2.712

Review 3.  Wear and osteolysis around total knee arthroplasty.

Authors:  Douglas D R Naudie; Deborah J Ammeen; Gerard A Engh; Cecil H Rorabeck
Journal:  J Am Acad Orthop Surg       Date:  2007-01       Impact factor: 3.020

4.  Long-term results of total knee arthroplasty in young patients with rheumatoid arthritis.

Authors:  Amy R Crowder; Gavan P Duffy; Robert T Trousdale
Journal:  J Arthroplasty       Date:  2005-10       Impact factor: 4.757

Review 5.  Long-term implant survivorship of cementless total knee arthroplasty: a systematic review of the literature and meta-analysis.

Authors:  Michael A Mont; Robert Pivec; Kimona Issa; Bhaveen H Kapadia; Aditya Maheshwari; Steven F Harwin
Journal:  J Knee Surg       Date:  2013-12-07       Impact factor: 2.757

6.  Total knee arthroplasty for patients younger than 55 years.

Authors:  C S Ranawat; D E Padgett; Y Ohashi
Journal:  Clin Orthop Relat Res       Date:  1989-11       Impact factor: 4.176

7.  Total knee replacement in young, active patients. Long-term follow-up and functional outcome.

Authors:  D R Diduch; J N Insall; W N Scott; G R Scuderi; D Font-Rodriguez
Journal:  J Bone Joint Surg Am       Date:  1997-04       Impact factor: 5.284

8.  Cementless and cemented total knee arthroplasty in patients younger than fifty five years. Which is better?

Authors:  Young-Hoo Kim; Jang-Won Park; Hyung-Mook Lim; Eun-Soo Park
Journal:  Int Orthop       Date:  2014-01-14       Impact factor: 3.075

Review 9.  Cementless fixation in total knee arthroplasty: past, present, and future.

Authors:  R Michael Meneghini; Arlen D Hanssen
Journal:  J Knee Surg       Date:  2008-10       Impact factor: 2.757

10.  Early failure of cementless porous tantalum monoblock tibial components.

Authors:  R Michael Meneghini; Brian C de Beaubien
Journal:  J Arthroplasty       Date:  2013-04-04       Impact factor: 4.757

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  5 in total

1.  CHANGES IN BONE MINERAL DENSITY AFTER TOTAL KNEE ARTHROPLASTY.

Authors:  Yasar Mahsut Dincel; Abdulkadir Sari; Cagatay Tekin; Burak Gunaydin; Mehmet Umit Cetin; Yunus Ziya Arslan
Journal:  Acta Ortop Bras       Date:  2020 Sep-Oct       Impact factor: 0.513

2.  Clinical outcomes and survivorship of cementless triathlon total knee arthroplasties: a systematic review.

Authors:  Brian J Carlson; Adam S Gerry; Jeffrey D Hassebrock; Zachary K Christopher; Mark J Spangehl; Joshua S Bingham
Journal:  Arthroplasty       Date:  2022-06-03

3.  Restricted kinematic alignment leads to uncompromised osseointegration of cementless total knee arthroplasty.

Authors:  Guillaume Laforest; Lazaros Kostretzis; Marc-Olivier Kiss; Pascal-André Vendittoli
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2021-01-16       Impact factor: 4.114

4.  A Short-Term Multicenter Analysis of Radiolucent Lines in a Single Uncemented Rotating Platform Implant for Total Knee Arthroplasty.

Authors:  Jason Desmarais; David Dalury; Thomas L Bernasek; David A Fisher; Ryan M Nunley; Marie-Claire Fickenscher; Robert S Gorab
Journal:  Arthroplast Today       Date:  2022-04-01

5.  Multiacquisition Variable-Resonance Image Combination Magnetic Resonance Imaging to Study Detailed Bone Apposition and Fixation of Cementless Knee System Compared to Cemented Total Knee Replacements.

Authors:  Gina M Mosich; Hollis G Potter; Matthew F Koff; Sara E Sacher; Mithun Mishu; Geoffrey H Westrich
Journal:  Arthroplast Today       Date:  2022-08-30
  5 in total

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