Literature DB >> 29297087

Biobrane dressing for paediatric burns in Singapore: a retrospective review.

Cong Fan1, Chong Han Pek2, Yong Chen Por1, Gale Jue Shuang Lim1.   

Abstract

INTRODUCTION: The ideal burn dressing for children should aim to alleviate pain, decrease length of hospital stay and minimise complications such as conversion and infection. The current literature is still inconclusive with regard to the gold standard burn dressing for the paediatric population.
METHODS: We retrospectively reviewed children with superficial partial thickness burns admitted to our paediatric burns unit from January 2014 to April 2015. A total of 30 patients were included in our study, of whom 13 had Biobrane® dressing. The remaining 17 patients were treated with conventional silver foam dressing (i.e. Biatain® Ag) and served as matched controls. Long-term follow-up scar evaluation was carried out at an average interval of two years after injury.
RESULTS: In the Biobrane group, the length of hospital stay was significantly shorter (Biobrane vs. silver foam: 4.76 ± 2.64 days vs. 8.88 ± 5.09 days; p = 0.01) and the infection rate was significantly lower (Biobrane vs. silver foam: 0% vs. 35.3%; p = 0.02). The Biobrane group had no hypergranulation or wound infection and did not require skin grafting. Long-term follow-up scar evaluation did not reveal any statistical difference between the patient groups at the two-year interval.
CONCLUSION: Paediatric patients with partial thickness burns treated with Biobrane dressing had shorter hospital stay and lower incidence of infection compared to those treated with conventional silver foam dressing. Biobrane and silver foam dressings did not demonstrate any significant difference in terms of long-term scar outcomes over an average follow-up duration of two years. Copyright: © Singapore Medical Association.

Entities:  

Keywords:  Biobrane; paediatric burns; silver dressing; skin substitutes; superficial partial thickness burns

Mesh:

Substances:

Year:  2018        PMID: 29297087      PMCID: PMC6056372          DOI: 10.11622/smedj.2017116

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  20 in total

1.  Clinical comparison of commercially available Biobrane preparations.

Authors:  J Y Yang; Y C Tsai; M S Noordhoff
Journal:  Burns       Date:  1989-06       Impact factor: 2.744

2.  The use of Biobrane by burn units in the United Kingdom: a national study.

Authors:  I S Whitaker; S Worthington; S Jivan; A Phipps
Journal:  Burns       Date:  2007-08-30       Impact factor: 2.744

3.  The properties of an "ideal" burn wound dressing--what do we need in daily clinical practice? Results of a worldwide online survey among burn care specialists.

Authors:  Harald F Selig; David B Lumenta; Michael Giretzlehner; Marc G Jeschke; Dominic Upton; Lars P Kamolz
Journal:  Burns       Date:  2012-05-08       Impact factor: 2.744

4.  Effectiveness of beta-glucan collagen for treatment of partial-thickness burns in children.

Authors:  S J Delatte; J Evans; A Hebra; W Adamson; H B Othersen; E P Tagge
Journal:  J Pediatr Surg       Date:  2001-01       Impact factor: 2.545

5.  A comparison of Biobrane vs. homograft for coverage of contaminated burn wounds.

Authors:  S Gonce; P Miskell; J P Waymack
Journal:  Burns Incl Therm Inj       Date:  1988-10

6.  Therapeutic efficacy of Biobrane in partial- and full-thickness thermal injury.

Authors:  T P McHugh; M C Robson; J P Heggers; L G Phillips; D J Smith; M C McCollum
Journal:  Surgery       Date:  1986-10       Impact factor: 3.982

Review 7.  Effect of silver on burn wound infection control and healing: review of the literature.

Authors:  Bishara S Atiyeh; Michel Costagliola; Shady N Hayek; Saad A Dibo
Journal:  Burns       Date:  2006-11-29       Impact factor: 2.744

8.  Biobrane versus duoderm for the treatment of intermediate thickness burns in children: a prospective, randomized trial.

Authors:  Christi Cassidy; Shawn D St Peter; Stephanie Lacey; Margie Beery; Paggy Ward-Smith; Ronald J Sharp; Daniel J Ostlie
Journal:  Burns       Date:  2005-07-14       Impact factor: 2.744

9.  A prospective randomised clinical pilot study to compare the effectiveness of Biobrane® synthetic wound dressing, with or without autologous cell suspension, to the local standard treatment regimen in paediatric scald injuries.

Authors:  F Wood; L Martin; D Lewis; J Rawlins; T McWilliams; S Burrows; S Rea
Journal:  Burns       Date:  2012-02-08       Impact factor: 2.744

10.  The patient and observer scar assessment scale: a reliable and feasible tool for scar evaluation.

Authors:  Lieneke J Draaijers; Fenike R H Tempelman; Yvonne A M Botman; Wim E Tuinebreijer; Esther Middelkoop; Robert W Kreis; Paul P M van Zuijlen
Journal:  Plast Reconstr Surg       Date:  2004-06       Impact factor: 4.730

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  3 in total

1.  Comparative effectiveness of Biobrane®, RECELL® Autologous skin Cell suspension and Silver dressings in partial thickness paediatric burns: BRACS randomised trial protocol.

Authors:  Anjana Bairagi; Bronwyn Griffin; Zephanie Tyack; Dimitrios Vagenas; Steven M McPhail; Roy Kimble
Journal:  Burns Trauma       Date:  2019-10-31

2.  No statistically significant difference in long term scarring outcomes of pediatric burns patients treated surgically vs. those treated conservatively.

Authors:  Riyam Mistry; Fadi Issa
Journal:  Front Surg       Date:  2022-09-09

Review 3.  From Grafts to Human Bioengineered Vascularized Skin Substitutes.

Authors:  Wasima Oualla-Bachiri; Ana Fernández-González; María I Quiñones-Vico; Salvador Arias-Santiago
Journal:  Int J Mol Sci       Date:  2020-11-02       Impact factor: 5.923

  3 in total

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