Literature DB >> 29296752

Lymphadenopathy driven by TCR-Vγ8Vδ1 T-cell expansion in FAS-related autoimmune lymphoproliferative syndrome.

Stefano Vavassori1, Jacob D Galson1,2, Johannes Trück1, Anke van den Berg3, Rienk Y J Tamminga4, Aude Magerus-Chatinet5, Olivier Pellé5, Ulrike Camenisch Gross6, Ewerton Marques Maggio6, Seraina Prader1, Lennart Opitz1,7, Ursina Nüesch1, Andrea Mauracher1, Benjamin Volkmer1, Oliver Speer1, Luzia Suda8, Benno Röthlisberger8, Dieter Robert Zimmermann6, Rouven Müller9, Arjan Diepstra3, Lydia Visser3, Eugenia Haralambieva5, Bénédicte Neven5, Frédéric Rieux-Laucat5, Jana Pachlopnik Schmid1,10.   

Abstract

FAS-dependent apoptosis in Vδ1 T cells makes the latter possible culprits for the lymphadenopathy observed in patients with FAS mutations.Rapamycin and methylprednisolone resistance should prompt clinicians to look for Vδ1 T cell proliferation in ALPS-FAS patients.

Entities:  

Year:  2017        PMID： 29296752      PMCID： PMC5728321          DOI： 10.1182/bloodadvances.2017006411

Source DB:  PubMed          Journal:  Blood Adv        ISSN： 2473-9529


  29 in total

Review 1.  New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome.

Authors:  David T Teachey
Journal:  Curr Opin Pediatr       Date:  2012-02       Impact factor: 2.856

Review 2.  T-cell antigen receptor genes and T-cell recognition.

Authors:  M M Davis; P J Bjorkman
Journal:  Nature       Date:  1988-08-04       Impact factor: 49.962

3.  Unusual organization and diversity of T-cell receptor alpha-chain genes.

Authors:  A C Hayday; D J Diamond; G Tanigawa; J S Heilig; V Folsom; H Saito; S Tonegawa
Journal:  Nature       Date:  1985 Aug 29-Sep 4       Impact factor: 49.962

4.  Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: preliminary results of a clinical cohort study and molecular observations.

Authors:  Jutte van der Werff Ten Bosch; Peter Schotte; Alice Ferster; Nadira Azzi; Thomas Boehler; Geneviève Laurey; Mikko Arola; Christian Demanet; Rudi Beyaert; Kris Thielemans; Jacques Otten
Journal:  Br J Haematol       Date:  2002-04       Impact factor: 6.998

5.  T cell receptor gamma delta repertoire is skewed in cerebrospinal fluid of multiple sclerosis patients: molecular and functional analyses of antigen-reactive gamma delta clones.

Authors:  S Nick; P Pileri; S Tongiani; Y Uematsu; L Kappos; G De Libero
Journal:  Eur J Immunol       Date:  1995-02       Impact factor: 5.532

6.  Differential regulation of miR-146a/FAS and miR-21/FASLG axes in autoimmune lymphoproliferative syndrome due to FAS mutation (ALPS-FAS).

Authors:  Lia Furlaneto Marega; Marcelo Ananias Teocchi; Maria Marluce Dos Santos Vilela
Journal:  Clin Exp Immunol       Date:  2016-05-24       Impact factor: 4.330

7.  Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome.

Authors:  Simon Völkl; Anne Rensing-Ehl; Andrea Allgäuer; Elisabeth Schreiner; Myriam Ricarda Lorenz; Jan Rohr; Christian Klemann; Ilka Fuchs; Volker Schuster; André O von Bueren; Nora Naumann-Bartsch; Eleonora Gambineri; Kathrin Siepermann; Robin Kobbe; Michaela Nathrath; Peter D Arkwright; Maurizio Miano; Klaus-Daniel Stachel; Markus Metzler; Klaus Schwarz; Anita N Kremer; Carsten Speckmann; Stephan Ehl; Andreas Mackensen
Journal:  Blood       Date:  2016-04-20       Impact factor: 22.113

8.  Expansion of selected V delta 1+ gamma delta T cells in systemic sclerosis patients.

Authors:  V V Yurovsky; P A Sutton; D H Schulze; F M Wigley; R A Wise; R F Howard; B White
Journal:  J Immunol       Date:  1994-07-15       Impact factor: 5.422

9.  Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial.

Authors:  Karen L Bride; Tiffaney Vincent; Kim Smith-Whitley; Michele P Lambert; Jack J Bleesing; Alix E Seif; Catherine S Manno; James Casper; Stephan A Grupp; David T Teachey
Journal:  Blood       Date:  2015-10-26       Impact factor: 22.113

10.  Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells.

Authors:  G De Libero; G Casorati; C Giachino; C Carbonara; N Migone; P Matzinger; A Lanzavecchia
Journal:  J Exp Med       Date:  1991-06-01       Impact factor: 14.307
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