Literature DB >> 29293943

Multidisciplinary management improves survival at 1 year after surgical treatment for non-small-cell lung cancer: a propensity score-matched study.

Nicola Tamburini1, Pio Maniscalco1, Sara Mazzara1, Elisa Maietti2, Alessandra Santini3, Nunzio Calia4, Antonio Stefanelli5, Antonio Frassoldati3, Ivan Santi6, Rosa Rinaldi7, Fares Nigim8, Riccardo Righi9, Stefania Pedrazzi3, Giorgio Cavallesco1.   

Abstract

OBJECTIVES: The management of patients affected by lung cancer requires the expertise of specialists from different disciplines. Although the advantages of multidisciplinary team discussions seem obvious, there are limited studies evaluating the influence of this approach on postoperative outcomes in non-small-cell lung cancer (NSCLC). The aim of this study is to examine the impact of a multidisciplinary approach on survival of patients undergoing surgery for NSCLC.
METHODS: A retrospective analysis was performed on consecutive patients who underwent surgery for NSCLC between January 2008 and December 2015. Data were compared between patients treated before the implementation of a multidisciplinary tumour board (MTB), between 2008 and 2012, and those who received treatment after the implementation of the MTB, between 2012 and 2015. Patients were matched one to one according to the discussion of the MTB and on the basis of a propensity score built using several patient characteristics. A propensity score-matched analysis was performed to compare patient outcomes.
RESULTS: A total of 246 patients were treated prior to the initiation of the MTB and 231 patients after the initiation of the MTB. Based on the propensity score, 2 well-matched groups of 170 patients were identified. Patients who were discussed at the MTB were noted to have better outcomes when compared with those who were not discussed at the MTB on different terms including complete staging evaluation, early tumour, node and metastasis (TNM) stages and 1-year survival rate.
CONCLUSIONS: Implementation of a multidisciplinary thoracic malignancy conference increased the 1-year survival rate of patients who underwent a surgical resection for NSCLC.

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Mesh:

Year:  2018        PMID: 29293943     DOI: 10.1093/ejcts/ezx464

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  11 in total

1.  Is multidisciplinary management possible in the treatment of lung cancer? A report from three Italian meetings.

Authors:  Davide Franceschini; Alessio Bruni; Paolo Borghetti; Niccolò Giaj-Levra; Sara Ramella; Lucio Buffoni; Serena Badellino; Maria Andolina; Camilla Comin; Emanuela Vattemi; Michela Bezzi; Marco Trovò; Antonio Passaro; Alessandra Bearz; Rita Chiari; Franchina Tindara; Katia Ferrari; Gaia Piperno; Andrea Riccardo Filippi; Domenico Genovesi; Vieri Scotti
Journal:  Radiol Med       Date:  2019-10-11       Impact factor: 3.469

Review 2.  Virtual Multidisciplinary Tumor Boards: A Narrative Review Focused on Lung Cancer.

Authors:  Vittorio Gebbia; Aurelia Guarini; Dario Piazza; Alessandro Bertani; Massimiliano Spada; Francesco Verderame; Concetta Sergi; Enrico Potenza; Ivan Fazio; Livio Blasi; Alba La Sala; Gianluca Mortillaro; Elena Roz; Roberto Marchese; Maurizio Chiarenza; Hector Soto-Parra; Maria Rosaria Valerio; Giuseppe Agneta; Carmela Amato; Helga Lipari; Sergio Baldari; Francesco Ferraù; Alfio Di Grazia; Gianfranco Mancuso; Sergio Rizzo; Alberto Firenze
Journal:  Pulm Ther       Date:  2021-06-04

3.  Patient and Health Care Professional Perspectives: A Case Study of the Lung Cancer Integrated Care Pathway.

Authors:  Francesca Bravi; Eugenio Di Ruscio; Antonio Frassoldati; Giorgio Narciso Cavallesco; Giorgia Valpiani; Anna Ferrozzi; Ulrich Wienand; Tiziano Carradori
Journal:  Int J Integr Care       Date:  2018-10-31       Impact factor: 5.120

4.  Lung Cancer Survival in Lithuania: Changes by Histology, Age, and Sex From 2003-2007 to 2008-2012.

Authors:  Vaida Gedvilaitė; Edvardas Danila; Saulius Cicėnas; Giedrė Smailytė
Journal:  Cancer Control       Date:  2019 Jan-Dec       Impact factor: 3.302

5.  Oral vinorelbine plus cisplatin with concomitant radiotherapy as induction therapy for stage III non-small cell lung cancer: Results of a single-arm prospective cohort study.

Authors:  Ping-Chih Hsu; John Wen-Chang Chang; Chun-Chieh Wang; Chen-Te Wu; Yu-Ching Lin; Chih-Liang Wang; Tin-Yu Lin; Shih-Hong Li; Yi-Chen Wu; Scott Chih-Hsi Kuo; Cheng-Ta Yang; Chien-Ying Liu; Chih-Hung Chen
Journal:  Thorac Cancer       Date:  2019-07-05       Impact factor: 3.500

6.  Higher number of multidisciplinary tumor board meetings per case leads to improved clinical outcome.

Authors:  Marius Freytag; Ulrich Herrlinger; Stefan Hauser; Franz G Bauernfeind; Maria A Gonzalez-Carmona; Jennifer Landsberg; Jens Buermann; Hartmut Vatter; Tobias Holderried; Thorsten Send; Martin Schumacher; Arne Koscielny; Georg Feldmann; Mario Heine; Dirk Skowasch; Niklas Schäfer; Benjamin Funke; Michael Neumann; Ingo G H Schmidt-Wolf
Journal:  BMC Cancer       Date:  2020-04-28       Impact factor: 4.430

7.  EGFR and non-small cell lung cancer: implications for surgical practice.

Authors:  Gonzalo Varela; Nuria M Novoa
Journal:  Ann Transl Med       Date:  2020-09

8.  Image analysis in posttreatment non-small cell lung cancer surveillance: specialists' interpretations reviewed by the thoracic multidisciplinary tumor board.

Authors:  Franco Gambazzi; Lukas D Frey; Matthias Bruehlmeier; Wolf-Dieter Janthur; Juerg Heuberger; Andres Spirig; Richard Williams; Roland Zweifel; Bettina Boerner; Gabrielo M Tini; Sarosh Irani
Journal:  Multidiscip Respir Med       Date:  2019-12-04

Review 9.  A review on the impact of lung cancer multidisciplinary care on patient outcomes.

Authors:  Monique Y Heinke; Shalini K Vinod
Journal:  Transl Lung Cancer Res       Date:  2020-08

10.  The Evolving Concept of Complete Resection in Lung Cancer Surgery.

Authors:  Ramón Rami-Porta
Journal:  Cancers (Basel)       Date:  2021-05-25       Impact factor: 6.639

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