Yonghua Bi1,2,3, Zepeng Yu1,2,3, Xinwei Han4,5,6, Jianzhuang Ren1,2,3. 1. Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China. 2. Interventional Institute of Zhengzhou University, Zhengzhou, China. 3. Interventional Therapy and Clinical Research Center of Henan Province, Zhengzhou, China. 4. Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China. dreamweaver08@126.com. 5. Interventional Institute of Zhengzhou University, Zhengzhou, China. dreamweaver08@126.com. 6. Interventional Therapy and Clinical Research Center of Henan Province, Zhengzhou, China. dreamweaver08@126.com.
Abstract
OBJECTIVE: To assess the feasibility, efficacy, and safety of agitation thrombolysis and catheter-directed thrombolysis (AT-CDT) in the treatment of normotensive patients with acute pulmonary thromboembolism (PTE). METHODS: A total of 37 consecutive patients of normotensive PTE were treated by AT-CDT between October 2011 and January 2016. Clinical outcomes and mortality were evaluated after the treatment, and follow-up was carried out after hospital discharge. RESULTS: AT-CDT was technically successful in 93.7% (36/37) patients, with one case died from respiratory failure during procedure. The clinical success rate was 91.9% (34/37), one patient died from intracranial hemorrhage 9 days after agitation, and one case showed no improvement. A total of 83.8% (31/37) cases were clinical cured and 8.1% (3/37) cases were relieved during hospitalization. Three cases died of respiratory failure caused by PTE, and two cases died of diseases unrelated to PTE (lung carcinoma/hemoptysis) during a 20-1524 days of follow-up. CONCLUSION: AT-CDT may be a feasible, effective, and safe treatment for normotensive patients with acute PTE.
OBJECTIVE: To assess the feasibility, efficacy, and safety of agitation thrombolysis and catheter-directed thrombolysis (AT-CDT) in the treatment of normotensive patients with acute pulmonary thromboembolism (PTE). METHODS: A total of 37 consecutive patients of normotensive PTE were treated by AT-CDT between October 2011 and January 2016. Clinical outcomes and mortality were evaluated after the treatment, and follow-up was carried out after hospital discharge. RESULTS:AT-CDT was technically successful in 93.7% (36/37) patients, with one case died from respiratory failure during procedure. The clinical success rate was 91.9% (34/37), one patient died from intracranial hemorrhage 9 days after agitation, and one case showed no improvement. A total of 83.8% (31/37) cases were clinical cured and 8.1% (3/37) cases were relieved during hospitalization. Three cases died of respiratory failure caused by PTE, and two cases died of diseases unrelated to PTE (lung carcinoma/hemoptysis) during a 20-1524 days of follow-up. CONCLUSION:AT-CDT may be a feasible, effective, and safe treatment for normotensive patients with acute PTE.
Authors: I Kürkciyan; G Meron; F Sterz; K Janata; H Domanovits; M Holzer; A Berzlanovich; H C Bankl; A N Laggner Journal: Arch Intern Med Date: 2000-05-22
Authors: Julia Klevanets; Vladimir Starodubtsev; Pavel Ignatenko; Olga Voroshilina; Pavel Ruzankin; Andrey Karpenko Journal: Ann Vasc Surg Date: 2017-05-10 Impact factor: 1.466