Literature DB >> 29290362

Early cardiac abnormalities in obese children and their relationship with adiposity.

María Mercedes Rodicio1, Vanessa Domenech de Miguel2, María Guinda Jiménez2, Secundino Cigarrán Guldrís3, María Montserrat López Franco2, Ana Estany Gestal4, María L Couce5, María Rosaura Leis Trabazo6.   

Abstract

OBJECTIVES: Childhood obesity rates are increasing as well as chronic disease and cardiovascular risk factors for patients at young ages. In this study, we evaluate the correlation between cardiac parameters, body mass index (BMI), and other body composition indicators in children and adolescents.
METHODS: In this cross-sectional study, we evaluated anthropometric measurements, bioelectrical impedance parameters, and echocardiographic measurements including the left ventricular mass (LVM), LVM index (LVMI), and left atrial diameter (LAD) in children and adolescents ages 7 to 15 y. We performed linear and multivariate regression analyses and analyzed the correlations between cardiac parameters, BMI, and other body composition parameters.
RESULTS: We analyzed 96 children and adolescents and found 40.6% to be obese and 29.2% overweight. LVMI and LAD indexed to height were significantly higher in individuals who were obese. LVMI increased significantly with increasing BMI (r = 0.717; P < 0.001), waist circumference (r = 0.670; P < 0.001), waist-to-height ratio (r = 0.650; P < 0.001), and body surface (r = 0.570; P < 0.001). Only BMI was significant in the multivariate analysis. LVMI was directly and positively correlated with fat mass (FM) and percentage of visceral and abdominal FM and negatively correlated with percentage of lean body mass. LAD was significantly correlated with body surface (r = 0.728; P < 0.001), BMI (r = 0.611; P < 0.001), waist circumference (r = 0.614; P < 0.001), and waist-to-height ratio (r = 0.341; P < 0.01). When indexed to height, LAD was only correlated with BMI and waist-to-height ratio.
CONCLUSIONS: Obesity is associated with cardiac disturbances at a very early age and these changes are closely related to the degree of adiposity. Cardiac structural parameters are significantly correlated with BMI and waist circumference in pediatric patients ages 7 to 15 y.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Body composition; Body mass index; Cardiac structural alterations; Childhood obesity; Left ventricular mass; Waist circumference

Mesh:

Year:  2017        PMID: 29290362     DOI: 10.1016/j.nut.2017.09.001

Source DB:  PubMed          Journal:  Nutrition        ISSN: 0899-9007            Impact factor:   4.008


  4 in total

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Authors:  Isabel María Blancas Sánchez; Cristhian H Aristizábal-Duque; Juan Fernández Cabeza; Pilar Aparicio-Martínez; Manuel Vaquero Alvarez; Martín Ruiz Ortíz; María Dolores Mesa Rubio; Francisco Javier Fonseca Pozo
Journal:  Pediatr Res       Date:  2022-03-23       Impact factor: 3.953

2.  Utility of Three Adiposity Indices for Identifying Left Ventricular Hypertrophy and Geometric Remodeling in Chinese Children.

Authors:  Huan Wang; Min Zhao; Costan G Magnussen; Bo Xi
Journal:  Front Endocrinol (Lausanne)       Date:  2021-11-16       Impact factor: 5.555

3.  Impact of Sex and Obesity on Echocardiographic Parameters in Children and Adolescents.

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Journal:  Pediatr Cardiol       Date:  2022-04-08       Impact factor: 1.838

4.  The impact of obesity on left ventricular hypertrophy and diastolic dysfunction in children and adolescents.

Authors:  Joanna Bartkowiak; Ernest Spitzer; Reto Kurmann; Fabian Zürcher; Peter Krähenmann; Victoria Garcia-Ruiz; Jorge Mercado; Christoph Ryffel; Sylvain Losdat; Nassip Llerena; Pedro Torres; Jonas Lanz; Martin Stocker; Ben Ren; Martin Glöckler; Thomas Pilgrim
Journal:  Sci Rep       Date:  2021-06-22       Impact factor: 4.379

  4 in total

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