| Literature DB >> 29289740 |
Alba Grifoni1, Daniela Weiskopf1, Cecilia S Lindestam Arlehamn1, Michael Angelo1, Shay Leary2, John Sidney1, April Frazier1, Elizabeth Phillips3, Simon Mallal3, Steven J Mack4, Rashmi Tippalagama5, Suraj Goonewardana5, Sunil Premawansa6, Gayani Premawansa7, Ananda Wijewickrama8, Aruna D De Silva9, Alessandro Sette10.
Abstract
DNA sequence-based typing at the HLA-A, -B, -C, -DPB1, -DQA1, -DQB1, and -DRB1 loci was performed on 714 healthy adult blood bank donors from Colombo, Sri Lanka, to characterize allele frequencies in support of studies on T cell immunity against pathogens, including Dengue virus. Deviations from Hardy Weinberg proportions were not detected at any locus. Several alleles were found in >30% of individuals, including the class II alleles DPB1 * 04:01, DPB1 * 02:01, DQB1 * 06:01 and DRB1 * 07:01, and the class I alleles A * 33:03 and A * 24:02. Genotype data will be available in the Allele Frequencies Net Database.Entities:
Keywords: Colombo, Sri Lanka; HLA alleles; HLA typing; Moors; Sinhalese; Tamil
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Year: 2017 PMID： 29289740 PMCID： PMC6378951 DOI： 10.1016/j.humimm.2017.12.007
Source DB: PubMed Journal: Hum Immunol ISSN： 0198-8859 Impact factor: 2.850