Audrey L Stokes1, Afif N Kulaylat1, Dorothy V Rocourt2, Christopher S Hollenbeak3, Walter Koltun4, Tolulope Falaiye5. 1. Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA. 2. Division of Pediatric Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA. 3. Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, PA, USA. Electronic address: chollenbeak@psu.edu. 4. Division of Colon and Rectal Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA. 5. Division of Pediatric Gastroenterology, Department of Pediatrics, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Abstract
BACKGROUND: Pediatric Crohn's disease (CD) is increasing in incidence globally. Trends in specific types of inpatient pediatric CD-related surgical procedures have not been widely reported. METHODS: Patients ≤20 years of age with CD were identified in the Kids' Inpatient Database for 2003, 2006, 2009, and 2012. Bowel resection, stoma creation, and perianal or percutaneous drainage procedures were identified using ICD-9 procedure codes, and trends were identified. Logistic regression was used to identify factors associated with surgical intervention and trends. RESULTS: Rates of overall bowel resection (including ileocolic resection, other small bowel resection, or other colon resection) did not change significantly over time. However, the odds of having a laparoscopic colon resection increased by 41% annually (p<0.001). Rates of subsequent ileostomy formation increased (odds ratio 1.09, p<0.001). Older age, male sex, fewer comorbidities, and treatment in large urban teaching hospitals were also associated with higher odds of undergoing bowel resection. CONCLUSIONS: This study noted a stable rate of all types of bowel resections and increase in post resection ileostomy formation in US pediatric inpatients with CD from 2003-2012. Other rates of many CD-related procedures have remained stable. Further studies correlating the effects of biologic agents on surgical rates are warranted. TYPE OF STUDY: Treatment Study LEVEL OF EVIDENCE: Level III.
BACKGROUND: Pediatric Crohn's disease (CD) is increasing in incidence globally. Trends in specific types of inpatient pediatric CD-related surgical procedures have not been widely reported. METHODS:Patients ≤20 years of age with CD were identified in the Kids' Inpatient Database for 2003, 2006, 2009, and 2012. Bowel resection, stoma creation, and perianal or percutaneous drainage procedures were identified using ICD-9 procedure codes, and trends were identified. Logistic regression was used to identify factors associated with surgical intervention and trends. RESULTS: Rates of overall bowel resection (including ileocolic resection, other small bowel resection, or other colon resection) did not change significantly over time. However, the odds of having a laparoscopic colon resection increased by 41% annually (p<0.001). Rates of subsequent ileostomy formation increased (odds ratio 1.09, p<0.001). Older age, male sex, fewer comorbidities, and treatment in large urban teaching hospitals were also associated with higher odds of undergoing bowel resection. CONCLUSIONS: This study noted a stable rate of all types of bowel resections and increase in post resection ileostomy formation in US pediatric inpatients with CD from 2003-2012. Other rates of many CD-related procedures have remained stable. Further studies correlating the effects of biologic agents on surgical rates are warranted. TYPE OF STUDY: Treatment Study LEVEL OF EVIDENCE: Level III.
Authors: Åsa H Everhov; Thordis Disa Kalman; Jonas Söderling; Caroline Nordenvall; Jonas Halfvarson; Anders Ekbom; Jonas F Ludvigsson; Ola Olén; Pär Myrelid Journal: Inflamm Bowel Dis Date: 2022-08-01 Impact factor: 7.290