Literature DB >> 29288448

Organoids as a Model to Study Infectious Disease.

Kristen A Engevik1, Andrea L Matthis1, Marshall H Montrose1, Eitaro Aihara2.   

Abstract

The advent of the gastric organoid culture system has provided a new model to emulate native epithelial tissue in vitro. Gastric organoids grow from isolated epithelial stem cells and develop into three dimensional structures that can be used to study host physiology. Here we describe current laboratory protocols for growing gastric organoids and the microinjection of pathogens such as Helicobacter pylori into the lumen of gastric organoids in order to study the cellular response following infection.

Entities:  

Keywords:  Fluorescent dye; Gastric organoids; Helicobacter pylori; Microinjection; Pathogens

Mesh：

Year:  2018        PMID： 29288448      PMCID： PMC8210541          DOI： 10.1007/978-1-4939-7604-1_8

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  9 in total

1.  Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Authors:  Toshiro Sato; Robert G Vries; Hugo J Snippert; Marc van de Wetering; Nick Barker; Daniel E Stange; Johan H van Es; Arie Abo; Pekka Kujala; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2009-03-29       Impact factor: 49.962

2.  Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells.

Authors:  Lydia E Wroblewski; M Blanca Piazuelo; Rupesh Chaturvedi; Michael Schumacher; Eitaro Aihara; Rui Feng; Jennifer M Noto; Alberto Delgado; Dawn A Israel; Yana Zavros; Marshall H Montrose; Noah Shroyer; Pelayo Correa; Keith T Wilson; Richard M Peek
Journal:  Gut       Date:  2014-08-14       Impact factor: 23.059

3.  Microinjection into Xenopus oocytes: equipment.

Authors:  M J Hitchcock; E I Ginns; C J Marcus-Sekura
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

4.  Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth.

Authors:  Melinda A Engevik; Eitaro Aihara; Marshall H Montrose; Gary E Shull; Daniel J Hassett; Roger T Worrell
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2013-09-26       Impact factor: 4.052

5.  Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile.

Authors:  Melinda A Engevik; Kristen A Engevik; Mary Beth Yacyshyn; Jiang Wang; Daniel J Hassett; Benjamin Darien; Bruce R Yacyshyn; Roger T Worrell
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-12-31       Impact factor: 4.052

6.  Human Clostridium difficile infection: altered mucus production and composition.

Authors:  Melinda A Engevik; Mary Beth Yacyshyn; Kristen A Engevik; Jiang Wang; Benjamin Darien; Daniel J Hassett; Bruce R Yacyshyn; Roger T Worrell
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-12-31       Impact factor: 4.052

7.  The use of murine-derived fundic organoids in studies of gastric physiology.

Authors:  Michael A Schumacher; Eitaro Aihara; Rui Feng; Amy Engevik; Noah F Shroyer; Karen M Ottemann; Roger T Worrell; Marshall H Montrose; Ramesh A Shivdasani; Yana Zavros
Journal:  J Physiol       Date:  2015-02-19       Impact factor: 5.182

8.  Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: the use of a novel in vitro model to study epithelial response to infection.

Authors:  Michael A Schumacher; Rui Feng; Eitaro Aihara; Amy C Engevik; Marshall H Montrose; Karen M Ottemann; Yana Zavros
Journal:  Helicobacter       Date:  2014-12-11       Impact factor: 5.753

9.  cAMP-stimulated ion currents in Xenopus oocytes expressing CFTR cRNA.

Authors:  S A Cunningham; R T Worrell; D J Benos; R A Frizzell
Journal:  Am J Physiol       Date:  1992-03
  9 in total
  7 in total

1.  Helicobacter pylori Uses the TlpB Receptor To Sense Sites of Gastric Injury.

Authors:  Hikaru Hanyu; Kristen A Engevik; Andrea L Matthis; Karen M Ottemann; Marshall H Montrose; Eitaro Aihara
Journal:  Infect Immun       Date:  2019-08-21       Impact factor: 3.441

2.  Generation of human antral and fundic gastric organoids from pluripotent stem cells.

Authors:  Taylor R Broda; Kyle W McCracken; James M Wells
Journal:  Nat Protoc       Date:  2019-01       Impact factor: 13.491

3.  In Pursuit of the Parietal Cell - An Evolution of Scientific Methodology and Techniques.

Authors:  Vanessa Baratta; Jason Own; Chiara Di Renzo; Jenna Ollodart; John P Geibel; Maria Barahona
Journal:  Front Physiol       Date:  2019-12-12       Impact factor: 4.566

4.  Extracting Insights From Temporal Data by Integrating Dynamic Modeling and Machine Learning.

Authors:  Richard Ballweg; Kristen A Engevik; Marshall H Montrose; Eitaro Aihara; Tongli Zhang
Journal:  Front Physiol       Date:  2020-08-12       Impact factor: 4.566

5.  TRPV6 channel mediates alcohol-induced gut barrier dysfunction and systemic response.

Authors:  Avtar S Meena; Pradeep K Shukla; Briar Bell; Francesco Giorgianni; Rebeca Caires; Carlos Fernández-Peña; Sarka Beranova; Eitaro Aihara; Marshall H Montrose; Mehdi Chaib; Liza Makowski; Indira Neeli; Marko Z Radic; Valeria Vásquez; Jonathan H Jaggar; Julio F Cordero-Morales; RadhaKrishna Rao
Journal:  Cell Rep       Date:  2022-06-14       Impact factor: 9.995

6.  "Neuro-Vascularized Skin Organoids": Novel Exploratory Research Tools in Leprosy.

Authors:  Keshav Sharma; Seema Chhabra; Maryada Sharma
Journal:  Indian Dermatol Online J       Date:  2022-05-05

Review 7.  Diabetes through a 3D lens: organoid models.

Authors:  Anastasia Tsakmaki; Patricia Fonseca Pedro; Gavin A Bewick
Journal:  Diabetologia       Date:  2020-03-27       Impact factor: 10.122
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.