Literature DB >> 29288386

Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury.

Eboni Chambers1,2, Sharon Rounds1,2, Qing Lu3,4.   

Abstract

Apoptosis plays an essential role in homeostasis and pathogenesis of a variety of human diseases. Endothelial cells are exposed to various environmental and internal stress and endothelial apoptosis is a pathophysiological consequence of these stimuli. Pulmonary endothelial cell apoptosis initiates or contributes to progression of a number of lung diseases. This chapter will focus on the current understanding of the role of pulmonary endothelial cell apoptosis in the development of emphysema and acute lung injury (ALI) and the factors controlling pulmonary endothelial life and death.

Entities:  

Keywords:  ARDS; Acute lung injury; Apoptosis; Autophagy; COPD; ER stress; Emphysema; Endothelial cells; Necroptosis; Necrosis; Pulmonary; Unfolded protein response

Mesh：

Year:  2018        PMID： 29288386      PMCID： PMC5930489          DOI： 10.1007/978-3-319-68483-3_4

Source DB:  PubMed          Journal:  Adv Anat Embryol Cell Biol        ISSN： 0301-5556            Impact factor:   1.231


  158 in total

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Journal:  J Immunol       Date:  2006-04-01       Impact factor: 5.422

Review 5.  Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury.

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Journal:  World J Gastroenterol       Date:  2010-03-21       Impact factor: 5.742

6.  alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Authors:  Irina Petrache; Iwona Fijalkowska; Terry R Medler; Jarrett Skirball; Pedro Cruz; Lijie Zhen; Horia I Petrache; Terence R Flotte; Rubin M Tuder
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7.  Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

Authors:  Yang Zhou; Jayasimha N Murthy; Dewan Zeng; Luiz Belardinelli; Michael R Blackburn
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Authors:  Gregor Simonis; Stephan Wiedemann; Dirk Joachim; Christof Weinbrenner; Rainer Marquetant; Ruth H Strasser
Journal:  Mol Cell Biochem       Date:  2009-03-20       Impact factor: 3.396

9.  Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis.

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10.  OBSTRUCTIVE LUNG DISEASE AND EXPOSURE TO BURNING BIOMASS FUEL IN THE INDOOR ENVIRONMENT.

Authors:  Gregory B Diette; Roberto A Accinelli; John R Balmes; A Sonia Buist; William Checkley; Paul Garbe; Nadia N Hansel; Vikas Kapil; Stephen Gordon; David K Lagat; Fuyuen Yip; Kevin Mortimer; Rogelio Perez-Padilla; Christa Roth; Julie M Schwaninger; Antonello Punturieri; James Kiley
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  19 in total

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Review 2.  Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms.

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Journal:  Stem Cell Res Ther       Date:  2019-06-13       Impact factor: 6.832

4.  Effect and mechanism of phospholipid scramblase 4 (PLSCR4) on lipopolysaccharide (LPS)-induced injury to human pulmonary microvascular endothelial cells.

Authors:  Xiaobin Liu; Dong Wang; Xiaoning Zhang; Meng Lv; Ge Liu; Changping Gu; Fan Yang; Yuelan Wang
Journal:  Ann Transl Med       Date:  2021-01

Review 5.  SARS-CoV-2 Mediated Endothelial Dysfunction: The Potential Role of Chronic Oxidative Stress.

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Journal:  Front Physiol       Date:  2021-01-15       Impact factor: 4.566

6.  Expression of DUSP12 Reduces Lung Vascular Endothelial Cell Damage in a Murine Model of Lipopolysaccharide-Induced Acute Lung Injury via the Apoptosis Signal-Regulating Kinase 1 (ASK1)-Jun N-Terminal Kinase Activation (JNK) Pathway.

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7.  Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways.

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Review 9.  Vascular Niche in Lung Alveolar Development, Homeostasis, and Regeneration.

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10.  STAT3-activated lncRNA XIST accelerates the inflammatory response and apoptosis of LPS-induced acute lung injury.

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