Zakaria Jalal1, Jean-François Piechaud2, Olivier Villemain3, Fidelio Sitenfane3, Sophie Malekzadeh-Milani3, Younes Boudjemline4. 1. Paediatric Cardiology, Centre de référence malformations cardiaques congénitales complexes, M3C, Necker Hospital for Sick Children, Assistance Publique des hôpitaux de Paris, 75105 Paris, France. Electronic address: jalalzakaria1@gmail.com. 2. Institut Hospitalier Jacques-Cartier, 91300 Massy, France. 3. Paediatric Cardiology, Centre de référence malformations cardiaques congénitales complexes, M3C, Necker Hospital for Sick Children, Assistance Publique des hôpitaux de Paris, 75105 Paris, France. 4. Paediatric Cardiology, Centre de référence malformations cardiaques congénitales complexes, M3C, Necker Hospital for Sick Children, Assistance Publique des hôpitaux de Paris, 75105 Paris, France; Université Paris V Descartes, 75006 Paris, France.
Abstract
BACKGROUND: Percutaneous coronary interventions (PCIs) are generally performed in adults with ischaemic heart disease, but reports of experience in the paediatric population are relatively limited. AIMS: To report indications, interventional techniques and procedural outcomes for PCI in children treated in two French institutions. METHODS: Medical records of all children in whom a PCI was attempted in two French tertiary institutions between 1998 and 2015 were systematically reviewed. Diagnostic procedures, including coronary angiograms, were excluded. RESULTS: A total of 40 PCIs were attempted in 29 patients (median age 6.5 years, range three days to 17.9 years). Nineteen procedures (47.5%) were performed on an emergency basis. A total of 36/40 coronary obstructions were successfully treated, with no immediate residual postintervention stenosis. Initial balloon angioplasty was performed for all lesions, with subsequent stent placement in 23 lesions. There were two periprocedural and five late deaths. After a median follow-up of 12 months (range 1 week to 115 months), freedom from death and reintervention at 36 months were 79% and 60%, respectively. Age<1 month, emergency procedure and balloon angioplasty without stent implantation were associated with shorter survival. CONCLUSION: PCI can be used in the paediatric population in a wide range of anatomical conditions; it may be effective in selected patients, but remains challenging when performed in emergency and/or in neonates.
BACKGROUND: Percutaneous coronary interventions (PCIs) are generally performed in adults with ischaemic heart disease, but reports of experience in the paediatric population are relatively limited. AIMS: To report indications, interventional techniques and procedural outcomes for PCI in children treated in two French institutions. METHODS: Medical records of all children in whom a PCI was attempted in two French tertiary institutions between 1998 and 2015 were systematically reviewed. Diagnostic procedures, including coronary angiograms, were excluded. RESULTS: A total of 40 PCIs were attempted in 29 patients (median age 6.5 years, range three days to 17.9 years). Nineteen procedures (47.5%) were performed on an emergency basis. A total of 36/40 coronary obstructions were successfully treated, with no immediate residual postintervention stenosis. Initial balloon angioplasty was performed for all lesions, with subsequent stent placement in 23 lesions. There were two periprocedural and five late deaths. After a median follow-up of 12 months (range 1 week to 115 months), freedom from death and reintervention at 36 months were 79% and 60%, respectively. Age<1 month, emergency procedure and balloon angioplasty without stent implantation were associated with shorter survival. CONCLUSION: PCI can be used in the paediatric population in a wide range of anatomical conditions; it may be effective in selected patients, but remains challenging when performed in emergency and/or in neonates.