| Literature DB >> 29280986 |
Shanthi Ameratunga1, Jacqueline Ramke2, Nicki Jackson3, Sandar Tin Tin4, Belinda Gabbe5,6.
Abstract
When prevention efforts fail, injured children require high-quality health services to support their recovery. Disparities in non-fatal injury outcomes, an indicator of health-care quality, have received minimal attention. We evaluated the extent to which general trauma follow-up studies published in the peer-reviewed scientific literature provide evidence of socially patterned inequities in health, functional or disability outcomes ≥4 weeks after childhood injuries. Using a systematic search, we identified 27 eligible cohort studies from 13 high-income countries. We examined the extent to which the reported health outcomes varied across the PROGRESS criteria: place of residence, race/ethnicity, occupation, gender/sex, religion, socio-economic status, and social capital. The available evidence on differential outcomes is limited as many studies were compromised by selection or retention biases that reduced the participation of children from demographic groups at increased risk of adverse outcomes, or the analyses mainly focused on variations in outcomes by sex. Given the limited research evidence, we recommend greater attention to systematic collection and reporting of non-fatal injury outcomes disaggregated by socio-demographic indicators in order to identify disparities where these exist and inform equity-focused interventions promoting the recovery of injured children.Entities:
Keywords: children; disability; disparities; ethnicity/race; functional outcomes; health inequalities; injury; prognosis; quality of life; socio-economic
Mesh:
Year: 2017 PMID: 29280986 PMCID: PMC5800142 DOI: 10.3390/ijerph15010043
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Figure 1Summary of study search and selection.
Summary of characteristics of included studies.
| Study Characteristics | Details |
|---|---|
| Country | Number of studies |
| The Netherlands | 6 |
| USA | 4 |
| Canada | 3 |
| Australia, France, Israel, Switzerland | 2 each |
| Austria, Belgium, Croatia, Spain, Sweden, UK | 1 each |
| Number of participants at final follow-up * | Number of participants |
| Median (inter-quartile range) | 146 (107–241) |
| Range | 28–700 |
| Proportion of eligible children in final follow-up * | % |
| Median (inter-quartile range) | 64 (57–73) |
| Range | 20–90 |
| Period of final follow-up (years since injury) | Number of studies |
| ≤0.5 | 7 |
| >0.5 ≤ 1 | 10 |
| >1 ≤ 3 | 4 |
| >3 | 6 |
| Tool used to measure outcome ** | Number of studies |
| A study-specific question/questionnaire | 8 |
| TACQOL | 5 |
| Child Health Questionnaire (CHQ)-PF50/PF28/CF87 | 5 |
| FIM/WeeFIM | 4 |
| Glasgow Outcome Scale/GOS-Extended | 3 |
| PEDSQL | 2 |
| EQ-5D, FS-II, IROS, KOSCHI, QWB, RAHC MOF, Rand Health Insurance, VABS, CBCL, SDQ, POPC | 1 each |
* Cannot determine in 5 studies; ** adds up to >27 as some studies used >1 tool. Abbreviations: TACQOL = Toegepast Natuurwetenschappelijk Onderzoek-Academisch Ziekenhuis Leiden (TNO-AZL) Children’s Quality of Life; CHQ = Child Health Questionnaire; PF = parent form; CF = child form; FIM = Functional Independence Measure; GOSE = Glasgow Outcome Scale Extended; PEDSQL = Pediatric Quality of Life Inventory; EQ-5D = EuroQoL – 5 Dimensions; FS-II = Functional Status II; IROS = ICF (International Classification of Functioning)-Related Outcome Score; KOSCHI = King’s Outcome Scale for Childhood Head Injury; QWB = Quality of Well Being; RAHC MOF = Royal Alexandra Hospital for Children Measure of Function; VABS = Vineland Adaptive Behaviour Scale; CBCL = Child Behaviour Checklist; SDQ = Strengths and Difficulties Questionnaire; POPC = Pediatric Overall Performance Category.
Specific characteristics of included studies including setting, measurement tools and follow-up features.
| Study (Alphabetical Order) | Country | Number of Children at Final Follow-Up | Proportion of Eligible Children Included at Final Follow-Up (%) | Period of Final Follow-Up (Years Since Injury) | Tool Used to Measure Outcome ** |
|---|---|---|---|---|---|
| Aitken 2002 [ | USA | 141 | 45.5 | 0.5 | CHQ-PF50, FIM/WeeFIM |
| Batailler 2014 [ | France | 127 | * | 1 | Study-specific question(s) |
| Davey 2005 [ | Australia | 241 | 57.4 | 1–2 | CHQ-PF50 |
| Dekker 2004 [ | The Netherlands | 100 | 71.9 | 2–7 | CHQ-CF87 |
| Gabbe 2011 [ | Australia | 144 | * | 1 | FIM, GOS, KOSCHI, CHQ-PF28, PEDSQL |
| Gofin 1999 [ | Israel | not reported | * | 0.5 | for 4–17 years 25 items questionnaire developed from International Classification of Impairments, Disabilities and Handicaps; study-specific questions for 0–3 years age group |
| Gofin 2007 [ | Israel | 549 | 59.4 | 0.42 | Study-specific question(s) |
| Holbrook 2007 [ | USA | 356 | 88.8 | 2 | Quality of wellbeing scale (QWB) |
| Janssens 2009 [ | The Netherlands | 28 | 70.0 | 6–8 | GOS, GOSE, VABS, CBCL, SDQ |
| Kendrick 2013 [ | UK | 164 | * | 1 | Study-specific question(s) |
| Landolt 2009 [ | Switzerland | 68 | 58.6 | 1 | TACQOL + study-specific question(s) |
| Macpherson 2003 [ | Canada | 357 | 73.0 | 0.5 | WeeFIM |
| Mestrovic 2013 [ | Croatia | not reported | * | 1 | RAHC MOF to assess HRQOL |
| Oloffson 2012 [ | Sweden | 341 | 81.2 | 1–1.67 | Study-specific question(s) |
| Polinder 2005 [ | The Netherlands | 365 | 29.9 | 0.75 | EuroQol (EQ-5D) |
| Pumar 2007 [ | Spain | 209 | * | 2–5 | POPC |
| Schalamon 2003 [ | Austria | 58 | 82.9 | 2–9 | GOS |
| Schneeberg 2017 [ | Canada | 161 | 19.5 | 1 | PEDSQL |
| Schweer 2006 [ | USA | 128 | 22.2 | 0.5 | CHQ-PF50 |
| Sturms 2002a [ | The Netherlands | 59 | 67.8 | 0.5–2.1 | FS-II, TACQOL |
| Sturms 2002b [ | The Netherlands | 211 | 64.5 | 1.5–3.4 | TACQOL |
| Sturms 2005 [ | The Netherlands | 51 | 35.7 | 0.5 | TACQOL |
| Valadka 2000 [ | Canada | 116 | 58.3 | not reported | Rand Health Insurance Study physical health scales + study question(s) |
| van de Voorde 2011 [ | Belgium | 146 | 63.8 | 1 | IROS |
| Vollrath 2005 [ | Switzerland | 107 | 60.1 | 1 | TACQOL |
| Winthrop 2005 [ | USA | 156 | 86.7 | 0.5 | FIM/WeeFIM |
| Yacoubovitch 1995 [ | France | 700 | * | 1 | Study-specific question(s) |
* Numerator or denominator not provided, ** Common abbreviations for named tools noted in full at the foot of Table 1.
Frequency of studies providing data on PROGRESS dimensions.
| Social Dimension | Baseline Participant Characteristics | Loss to Follow-Up | Disaggregated/Unadjusted Outcomes | Adjusted Outcomes | |||
|---|---|---|---|---|---|---|---|
| Reported | Reported | Difference Found * | Reported | Difference Found * | Reported | Difference Found * | |
| P Place of residence | 1 (4) | - | - | 2 (7) | 1 | 1 (4) | 1 |
| R Race/ethnicity/culture/language | 7 (26) | 1 (4) | - | 2 (7) | - | 2 (7) | - |
| O Occupation | 2 (7) | 1 (4) | 1 | 1 (4) | - | - | - |
| G Gender/sex | 24 (89) | 9 (33) | 1 | 8 (30) | 2 | 11 (41) | 3 |
| R Religion | - | - | - | - | - | - | - |
| E Education | 1 (4) | - | - | 1 (4) | 1 | 2 (7) | 1 |
| S Socio-economic status | 4 (15) | 1 (4) | 1 | 2 (7) | - | 1 (4) | - |
| S Social capital | 2 (7) | - | - | - | - | 1 (4) | - |
| 25 (93) | 10 (37) | 10 (37) | 13 (48) | ||||
* Reported differences between sub-groups are summarized in Table 4.
General trauma follow-up studies in childhood identifying influences on, or significant variations in, health outcomes by PROGRESS criteria.
| Explanatory Factor | PROGRESS Criteria | Study | Reported Difference(s) in Children | |
|---|---|---|---|---|
| Propensity of being lost to follow-up (a key factor that could influence investigations of predictors of differential health outcomes) | Occupation | Batailler 2014 [ | Non-respondents were reported as more likely to be of lower socio-economic occupational level; no related data or statistics provided | |
| Gender | Yacoubovitch 1995 [ | 8% of boys and 13% of girls were lost to follow-up; no statistics provided | ||
| Socio-economic status (SES) | Schneeberg 2017 [ | Participants in low-income families less available for 12 months follow-up interview. | ||
| 5 (highest-income quintile) | 1.0 (reference) | |||
| 4 | 0.5 (0.2–1.4) | |||
| 3 | 1.8 (0.6–4.9) | |||
| 2 | 0.7 (0.3–1.8) | |||
| 1 (lowest income quintile) | 0.3 (0.1–0.7) | |||
| Unadjusted outcomes | Place | Kendrick 2013 [ | Variations in recovery at 12 months by study site | |
| Nottingham | 1.00 | |||
| Bristol | 1.17 (0.98–1.41) | |||
| Swansea | 1.22 (1.05–1.40) | |||
| Surrey | 1.21 (1.05–1.39) | |||
| Gender | Yacoubovitch 1995 [ | 20% girls compared with 12% boys had not recovered at 12 months ( | ||
| Polinder 2005 [ | Girls more likely than boys to have sub-optimal functioning at 12 months | |||
| Boy | 1.0 | |||
| Girl | 2.9 (1.0–9.9) | |||
| Education | Sturms 2002b [ | Predictors of lower health-related quality of life at a mean follow-up period of 2.4 years post-injury | ||
| Lower educational level of father ( | ||||
| Lower educational level of mother ( | ||||
| Adjusted outcomes | Place | Kendrick 2013 [ | Recovery at 12 months: Relative Risk (95% CI) | |
| Nottingham | 1.00 | |||
| Bristol | 1.01 (0.88–1.16) | |||
| Swansea | 1.12 (0.99–1.27) | |||
| Surrey | 1.15 (1.02–1.30) | |||
| Gender | Kendrick 2013 [ | Recovery at 12 months: Relative Risk (95% CI) | ||
| Girls | 1.0 | |||
| Boys | 1.15 (1.03–1.27) | |||
| Polinder 2005 [ | Sub-optimal functioning at 12 months | |||
| Boy | 1.0 | |||
| Girl | 3.0 (1.0–11.0) | |||
| Holbrook 2007 [ | Results section notes the Quality of Well Being scores at 18-month follow-up were lower in adolescent girls than in boys; no data provided | |||
| Education | Sturms 2002b [ | Lower education of fathers and mothers (highly correlated) were significant explanatory variables of lower health-related quality of life of children. Estimate for mothers’ educational level provided ( | ||