| Literature DB >> 29280636 |
Zhu-Bao Yin1, Jian-Heng Ye1, Wen-Jun Zhou1,2, Yi-Han Zhang1, Li Ding1, Yong-Yuan Gui1, Si-Shun Yan1, Jing Li1, Da-Gang Yu1.
Abstract
A selective oxy-difluoroalkylation of allylamines with carbon dioxide (CO2) via visible-light photoredox catalysis is reported. These multicomponent reactions are efficient and environmentally friendly to generate a series of important 2-oxazolidinones with functionalized difluoroalkyl groups. The good functional group tolerance, broad substrate scope, easy scalability, mild reaction conditions, and facile functionalization of products provide great potential for application in organic synthesis and pharmaceutical chemistry.Entities:
Year: 2017 PMID： 29280636 DOI： 10.1021/acs.orglett.7b03551
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005