Literature DB >> 29280367

Intravitreal Bevacizumab in Diabetic Retinopathy. Recommendations from the Pan-American Collaborative Retina Study Group (PACORES): The 2016 Knobloch Lecture.

J Fernando Arevalo1, T Y Alvin Liu1.   

Abstract

The advent of intravitreal anti-vascular endothelial growth factor (anti-VEGF) medications has revolutionized the treatment of diabetic eye diseases. Herein, we report the outcomes of clinical studies carried out by the Pan-American Collaborative Retina Study Group (PACORES), with a specific focus on the efficacy of intravitreal bevacizumab in the management of diabetic macular edema and proliferative diabetic retinopathy. We will also discuss the use of intravitreal bevacizumab as a preoperative, adjuvant therapy before vitrectomy for proliferative diabetic retinopathy. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

Entities:  

Keywords:  bevacizumab; diabetic macular edema; intravitreal injections; proliferative diabetic retinopathy; tractional retinal detachment

Mesh:

Substances:

Year:  2017        PMID: 29280367     DOI: 10.22608/APO.2017466

Source DB:  PubMed          Journal:  Asia Pac J Ophthalmol (Phila)        ISSN: 2162-0989


  5 in total

1.  Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway.

Authors:  Sally L Elshaer; Abdulrahman Alwhaibi; Riyaz Mohamed; Tahira Lemtalsi; Maha Coucha; Frank M Longo; Azza B El-Remessy
Journal:  Diabetologia       Date:  2019-05-09       Impact factor: 10.122

Review 2.  The Evolving Treatment of Diabetic Retinopathy.

Authors:  Sam E Mansour; David J Browning; Keye Wong; Harry W Flynn; Abdhish R Bhavsar
Journal:  Clin Ophthalmol       Date:  2020-03-04

3.  Modulation of p75NTR on Mesenchymal Stem Cells Increases Their Vascular Protection in Retinal Ischemia-Reperfusion Mouse Model.

Authors:  Sally L Elshaer; Hang-Soo Park; Laura Pearson; William D Hill; Frank M Longo; Azza B El-Remessy
Journal:  Int J Mol Sci       Date:  2021-01-15       Impact factor: 5.923

4.  Intravitreal aflibercept for the treatment of patients with diabetic macular edema in routine clinical practice in Latin America: the AQUILA study.

Authors:  Francisco J Rodríguez; Lihteh Wu; Arnaldo F Bordon; Martin Charles; JinKyung Lee; Tobias Machewitz; Margarete Mueller; Gabriela Del Carmen Gay; Jans Fromow-Guerra
Journal:  Int J Retina Vitreous       Date:  2022-08-02

Review 5.  A Paradigm Shift in the Management Approaches of Proliferative Diabetic Retinopathy: Role of Anti-VEGF Therapy.

Authors:  Rajiv Raman; Kim Ramasamy; Utkarsh Shah
Journal:  Clin Ophthalmol       Date:  2022-09-08
  5 in total

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