Literature DB >> 29279808

Anaplastic Carcinoma of the Pancreas: A Rare Clinical Entity.

Erkan Oymaci1, Savas Yakan1, Mehmet Yildirim1, Asuman Argon2, Ozan Namdaroglu1.   

Abstract

Anaplastic carcinoma of the pancreas (ACP) is a very rare histologic subtype of pancreatic cancer and associated with more aggressive and poor prognosis than pancreatic ductal adenocarcinoma. We aimed to review this rare entity and discuss its clinical features, diagnosis and therapy. We presented a case of a 63-year-old male patient that diagnosed as ACP with cyst formation at a tertiary medical center with a detailed review of the current medical literature. We performed pancreaticoduodenectomy operation with lymph node dissection after diagnosis. Any complication after surgery was not observed. Anaplastic pancreas carcinomas are associated with poor survival when compared to invasive ductal adenocarcinomas. Clinical, radiological, laboratory and histological features may be helpful in making differential diagnosis and should be kept in mind in the diagnosis of this rare pancreatic malignancy.

Entities:  

Keywords:  anaplastic carcinoma; pancreas; surgery

Year:  2017        PMID: 29279808      PMCID: PMC5736168          DOI: 10.7759/cureus.1782

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  8 in total

Review 1.  A clinicopathologic and immunohistochemical study of 35 anaplastic carcinomas of the pancreas with a review of the literature.

Authors:  E Paal; L D Thompson; R A Frommelt; R M Przygodzki; C S Heffess
Journal:  Ann Diagn Pathol       Date:  2001-06       Impact factor: 2.090

2.  Pleomorphic carcinoma of the pancreas: an analysis of 15 cases.

Authors:  T P Tschang; R Garza-Garza; J M Kissane
Journal:  Cancer       Date:  1977-05       Impact factor: 6.860

Review 3.  Giant cell tumor of the pancreas: a pathological diagnosis with poor prognosis.

Authors:  Ashish Singhal; Stan S Shrago; Shi-Feng Li; Yi Huang; Vivek Kohli
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2010-08

4.  Morphological study of 391 cases of exocrine pancreatic tumours with special reference to the classification of exocrine pancreatic carcinoma.

Authors:  J Chen; S I Baithun
Journal:  J Pathol       Date:  1985-05       Impact factor: 7.996

5.  Atypical exocrine and endocrine pancreatic tumors (anaplastic, small cell, and giant cell types): CT and pathologic features in 14 patients.

Authors:  T Ichikawa; M P Federle; S Ohba; K Ohtomo; A Sugiyama; H Fujimoto; H Haradome; T Araki
Journal:  Abdom Imaging       Date:  2000 Jul-Aug

6.  A case report of anaplastic carcinoma of the pancreas with remarkable intraductal tumor growth into the main pancreatic duct.

Authors:  Mitsuyoshi Okazaki; Isamu Makino; Hirohisa Kitagawa; Shinichi Nakanuma; Hironori Hayashi; Hisatoshi Nakagawara; Tomoharu Miyashita; Hidehiro Tajima; Hiroyuki Takamura; Tetsuo Ohta
Journal:  World J Gastroenterol       Date:  2014-01-21       Impact factor: 5.742

7.  Clinical outcomes for anaplastic pancreatic cancer: a population-based study.

Authors:  Clancy J Clark; Rondell P Graham; Janani S Arun; W Scott Harmsen; Kaye M Reid-Lombardo
Journal:  J Am Coll Surg       Date:  2012-11       Impact factor: 6.113

Review 8.  Anaplastic carcinoma of the pancreas: Case report and literature review of reported cases in Japan.

Authors:  Sojun Hoshimoto; Junichi Matsui; Ryohei Miyata; Yutaka Takigawa; Jun Miyauchi
Journal:  World J Gastroenterol       Date:  2016-10-14       Impact factor: 5.742

  8 in total

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