Filippo Graziani1,2, Stefano Gennai1,2, Anna Solini1,2,3, Morena Petrini1,2. 1. Department of Surgical, Medical and Molecular Pathology, Critical Care Medicine, University of Pisa, Pisa, Italy. 2. Sub-Unit of Periodontology, Halitosis and Periodontal Medicine, University Hospital of Pisa, Pisa, Italy. 3. Unit of Internal Medicine, University Hospital of Pisa, Pisa, Italy.
Abstract
AIM: To update the available evidence on the impact of periodontitis on diabetes control, incidence and complications. METHODS: Observational studies on the effect of periodontitis on diabetes, published after 2012, were identified through electronic databases and hand-searched journals. Findings were summarized by evidence tables, using PRISMA statement. Quality of the included studies was evaluated through the Newcastle Ottawa scale. RESULTS: Healthy individuals with periodontitis exhibit a poor glycaemic control and a higher risk of developing diabetes. Individuals affected by diabetes show a deterioration of glycaemic control if also affected by periodontitis and significantly higher prevalence of diabetes-related complications. Limited evidence is available on gestational diabetes and type 1 diabetes. CONCLUSIONS: Periodontitis has a significant impact on diabetes control, incidence and complications. Nevertheless, the heterogeneity and quality of the included publications suggest that caution should be exercised when interpreting the data and that there remains an important need for additional evidence.
AIM: To update the available evidence on the impact of periodontitis on diabetes control, incidence and complications. METHODS: Observational studies on the effect of periodontitis on diabetes, published after 2012, were identified through electronic databases and hand-searched journals. Findings were summarized by evidence tables, using PRISMA statement. Quality of the included studies was evaluated through the Newcastle Ottawa scale. RESULTS: Healthy individuals with periodontitis exhibit a poor glycaemic control and a higher risk of developing diabetes. Individuals affected by diabetes show a deterioration of glycaemic control if also affected by periodontitis and significantly higher prevalence of diabetes-related complications. Limited evidence is available on gestational diabetes and type 1 diabetes. CONCLUSIONS:Periodontitis has a significant impact on diabetes control, incidence and complications. Nevertheless, the heterogeneity and quality of the included publications suggest that caution should be exercised when interpreting the data and that there remains an important need for additional evidence.
Authors: Nicolas Noetzel; Anna Maria Meyer; Giacomo Siri; Lena Pickert; Annika Heeß; Joshua Verleysdonk; Thomas Benzing; Alberto Pilotto; Anna Greta Barbe; Maria Cristina Polidori Journal: Eur Geriatr Med Date: 2020-11-18 Impact factor: 1.710