Literature DB >> 29277462

Randomized Controlled Trial to Prevent Infant Overweight in a High-Risk Population.

Elizabeth Reifsnider1, David P McCormick2, Karen W Cullen3, Michael Todd1, Michael W Moramarco1, Martina R Gallagher4, Lucia Reyna1.   

Abstract

OBJECTIVES: Infants are at risk of overweight. Infant overweight predisposes child, adolescent, and adult to obesity. We hypothesized that parent education, initiated prenatally and provided in the home, would reduce the incidence of infant overweight at age 12 months.
METHODS: Pregnant obese Latina women were recruited at Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and randomized to intervention versus control. Intervention subjects received home visits by trained Spanish-fluent community health workers who provided counseling on infant growth, breastfeeding, nutrition, child development, sleep, physical activity, and safety. Promotoras did not visit the control subjects. A research assistant collected outcome data on all subjects.
RESULTS: Compared to controls, parent education did not reduce infant overweight. Infant overweight developed rapidly and was present in 46% of infants by age 6 months. Infants overweight at 6 months were likely to be overweight at age 12 months (r = 0.60, P < .0001). Overweight was more common in formula-fed infants at ages 6 months (P < .06) and 12 months (P = .005). Breastfeeding was less common in families with employed mothers (P = .02) and unemployed fathers (P < .01), but the father living with the mother at the time of the prenatal visit predicted successful breastfeeding at infant age 2 months (P < .003). Compared to formula feeding, overweight at age 12 months was 2.7 times less likely for infants breastfed for ≥2 months (P = .01).
CONCLUSIONS: The lack of success of the intervention may be explained in part by a high cesarean section rate in the intervention group, food and employment insecurity, and confounding by WIC breastfeeding promotion, which was available to all mothers. Breastfeeding was the most important mediator of infant overweight. The study supports efforts by WIC to vigorously promote breastfeeding.
Copyright © 2018 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  child; infant; intervention; obesity; prevention

Mesh:

Year:  2017        PMID: 29277462      PMCID: PMC5889724          DOI: 10.1016/j.acap.2017.12.007

Source DB:  PubMed          Journal:  Acad Pediatr        ISSN: 1876-2859            Impact factor:   3.107


  34 in total

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2.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

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Authors:  Christen M Lefebvre; Rita Marie John
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4.  How Did They Grow: An Intervention to Reduce Stunted Growth in Low-Income Mexican-American Children.

Authors:  Elizabeth Reifsnider; Cha-Nam Shin; Michael Todd; Mihyun Jeong; Martina Gallagher; Michael Moramarco
Journal:  Res Nurs Health       Date:  2016-02-24       Impact factor: 2.228

5.  Sustainability of Effects of an Early Childhood Obesity Prevention Trial Over Time: A Further 3-Year Follow-up of the Healthy Beginnings Trial.

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6.  Trends and racial/ethnic disparities in severe obesity among US children and adolescents, 1976-2006.

Authors:  Y Claire Wang; Steven L Gortmaker; Elsie M Taveras
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7.  Birth weight and subsequent body mass index in children: an international cross-sectional study.

Authors:  E A Mitchell; A W Stewart; I Braithwaite; R J Hancox; R Murphy; C Wall; R Beasley
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8.  Associations of infant feeding with trajectories of body composition and growth.

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9.  Lower breastfeeding rates persist among the Special Supplemental Nutrition Program for Women, Infants, and Children participants, 1978-2003.

Authors:  Alan S Ryan; Wenjun Zhou
Journal:  Pediatrics       Date:  2006-04       Impact factor: 7.124

10.  Trends in Weight-for-Length Among Infants in WIC From 2000 to 2014.

Authors:  David S Freedman; Andrea J Sharma; Heather C Hamner; Liping Pan; Anthony Panzera; Ray B Smith; Heidi M Blanck
Journal:  Pediatrics       Date:  2016-12-13       Impact factor: 7.124

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  7 in total

Review 1.  Addressing obesity in the first 1000 days in high risk infants: Systematic review.

Authors:  Chris Rossiter; Heilok Cheng; Jessica Appleton; Karen J Campbell; Elizabeth Denney-Wilson
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2.  Calories, Caffeine and the Onset of Obesity in Young Children.

Authors:  David P McCormick; Lucia Reyna; Elizabeth Reifsnider
Journal:  Acad Pediatr       Date:  2020-02-17       Impact factor: 3.107

3.  Recruitment and retention of underrepresented and vulnerable populations to research.

Authors:  Shelby L Langer; Felipe González Castro; Angela Chia-Chen Chen; Kelly Cue Davis; Rodney P Joseph; Wonsun Sunny Kim; Linda Larkey; Rebecca E Lee; Megan E Petrov; Elizabeth Reifsnider; Shawn D Youngstedt; Gabriel Q Shaibi
Journal:  Public Health Nurs       Date:  2021-07-08       Impact factor: 1.462

4.  Factors affecting the growth of children till the age of three years with overweight whose mothers have diabetes mellitus: A population-based cohort study.

Authors:  Yuan-Der Huang; Yun-Ru Luo; Meng-Chih Lee; Chih-Jung Yeh
Journal:  BMC Pediatr       Date:  2021-07-02       Impact factor: 2.125

5.  Interventions for supporting the initiation and continuation of breastfeeding among women who are overweight or obese.

Authors:  Frankie J Fair; Gemma L Ford; Hora Soltani
Journal:  Cochrane Database Syst Rev       Date:  2019-09-17

6.  Home-based intervention for non-Hispanic black families finds no significant difference in infant size or growth: results from the Mothers & Others randomized controlled trial.

Authors:  Heather M Wasser; Amanda L Thompson; Chirayath M Suchindran; Barbara D Goldman; Eric A Hodges; Meredith J Heinig; Margaret E Bentley
Journal:  BMC Pediatr       Date:  2020-08-18       Impact factor: 2.125

Review 7.  A Review of Registered Randomized Controlled Trials for the Prevention of Obesity in Infancy.

Authors:  Seema Mihrshahi; Danielle Jawad; Louise Richards; Kylie E Hunter; Mahalakshmi Ekambareshwar; Anna Lene Seidler; Louise A Baur
Journal:  Int J Environ Res Public Health       Date:  2021-03-02       Impact factor: 3.390

  7 in total

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