Literature DB >> 29276782

Stemness-Related Markers in Cancer.

Wenxiu Zhao1, Yvonne Li2, Xun Zhang1.   

Abstract

Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth, and resistance to therapy. Like embryonic and adult stem cells, CSCs express markers that are not expressed in normal somatic cells and are thus thought to contribute towards a 'stemness' phenotype. This review summarizes the current knowledge of stemness-related markers in human cancers, with a particular focus on important transcription factors, protein surface markers and signaling pathways.

Entities:  

Year:  2017        PMID: 29276782      PMCID: PMC5737740          DOI: 10.4103/ctm.ctm_69_16

Source DB:  PubMed          Journal:  Cancer Transl Med        ISSN: 2395-3012


  141 in total

1.  Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Authors:  Anna V Molofsky; Ricardo Pardal; Toshihide Iwashita; In-Kyung Park; Michael F Clarke; Sean J Morrison
Journal:  Nature       Date:  2003-10-22       Impact factor: 49.962

2.  Expression analysis of stem cell-related genes reveal OCT4 as a predictor of poor clinical outcome in medulloblastoma.

Authors:  Carolina Oliveira Rodini; Daniela Emi Suzuki; Najsla Saba-Silva; Andréa Cappellano; Jorge Estefano Santana de Souza; Sérgio Cavalheiro; Silvia Regina Caminada Toledo; Oswaldo Keith Okamoto
Journal:  J Neurooncol       Date:  2011-07-02       Impact factor: 4.130

3.  Overexpression of Nanog protein is associated with poor prognosis in gastric adenocarcinoma.

Authors:  Ting Lin; Yan-Qing Ding; Jian-Ming Li
Journal:  Med Oncol       Date:  2011-02-20       Impact factor: 3.064

4.  Loss of cytoplasmic KLF4 expression is correlated with the progression and poor prognosis of nasopharyngeal carcinoma.

Authors:  Zhen Liu; Huiling Yang; Weiren Luo; Qingping Jiang; Chunping Mai; Yan Chen; Yan Zhen; Xiaoli Yu; Xiaobin Long; Weiyi Fang
Journal:  Histopathology       Date:  2013-06-12       Impact factor: 5.087

5.  Biology and plasticity of CD133+ hematopoietic stem cells.

Authors:  Rupert Handgretinger; Paul R Gordon; Thasia Leimig; Xiaohua Chen; Hans-Jorg Buhring; Dietrich Niethammer; Selim Kuci
Journal:  Ann N Y Acad Sci       Date:  2003-05       Impact factor: 5.691

Review 6.  Oncogenic roles and drug target of CXCR4/CXCL12 axis in lung cancer and cancer stem cell.

Authors:  Zhidong Wang; Jian Sun; Yeqian Feng; Xiaocai Tian; Bin Wang; Yong Zhou
Journal:  Tumour Biol       Date:  2016-04-14

7.  The spatial distribution of LGR5+ cells correlates with gastric cancer progression.

Authors:  Eva Simon; Diana Petke; Christine Böger; Hans-Michael Behrens; Viktoria Warneke; Matthias Ebert; Christoph Röcken
Journal:  PLoS One       Date:  2012-04-18       Impact factor: 3.240

Review 8.  Targeting the canonical Wnt/β-catenin pathway in hematological malignancies.

Authors:  Eishi Ashihara; Tetsuya Takada; Taira Maekawa
Journal:  Cancer Sci       Date:  2015-04-01       Impact factor: 6.716

Review 9.  Embryonic stem cell markers.

Authors:  Wenxiu Zhao; Xiang Ji; Fangfang Zhang; Liang Li; Lan Ma
Journal:  Molecules       Date:  2012-05-25       Impact factor: 4.411

10.  Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer.

Authors:  Xiao-Yang Wang; Huina Yu; R Ilona Linnoila; Laodong Li; Dangyu Li; Biwen Mo; Hideyuki Okano; Luiz O F Penalva; Robert I Glazer
Journal:  Oncotarget       Date:  2013-05
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  44 in total

Review 1.  Role of OCT4 in cancer stem-like cells and chemotherapy resistance.

Authors:  Ismail S Mohiuddin; Sung-Jen Wei; Min H Kang
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2019-03-21       Impact factor: 5.187

Review 2.  The role of metabolic ecosystem in cancer progression - metabolic plasticity and mTOR hyperactivity in tumor tissues.

Authors:  Anna Sebestyén; Titanilla Dankó; Dániel Sztankovics; Dorottya Moldvai; Regina Raffay; Catherine Cervi; Ildikó Krencz; Viktória Zsiros; András Jeney; Gábor Petővári
Journal:  Cancer Metastasis Rev       Date:  2022-01-14       Impact factor: 9.264

3.  Testicular cancer in mice: interplay between stem cells and endocrine insults.

Authors:  Ankita Kaushik; Deepa Bhartiya
Journal:  Stem Cell Res Ther       Date:  2022-06-08       Impact factor: 8.079

4.  Association of early changes of circulating cancer stem-like cells with survival among patients with metastatic breast cancer.

Authors:  Pei-Hung Chang; Chun-Hui Lee; Tyler Min-Hsien Wu; Kun-Yun Yeh; Hung-Ming Wang; Wen-Kuan Huang; Sheng-Chieh Chan; Wen-Chi Chou; Feng-Che Kuan; Hsuan-Chih Kuo; Yung-Chia Kuo; Ching-Chih Hu; Jason Chia-Hsun Hsieh
Journal:  Ther Adv Med Oncol       Date:  2022-07-15       Impact factor: 5.485

Review 5.  PAX8 in the Junction between Development and Tumorigenesis.

Authors:  Reli Rachel Kakun; Zohar Melamed; Ruth Perets
Journal:  Int J Mol Sci       Date:  2022-07-03       Impact factor: 6.208

6.  Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers.

Authors:  Boya Li; Yu Feng; Qiaoyun Hou; Yan Fu; Yongzhang Luo
Journal:  Int J Mol Sci       Date:  2022-06-28       Impact factor: 6.208

7.  Identification of a novel splice variant of the human musashi-1 gene.

Authors:  Lin Ma; Yating Shan; Heliang Ma; Ihab Elshoura; Muhammad Nafees; Kaiyong Yang; Wu Yin
Journal:  Oncol Lett       Date:  2018-08-13       Impact factor: 2.967

8.  SOX2/SALL4 stemness axis modulates Notch signaling genes to maintain self-renewal capacity of esophageal squamous cell carcinoma.

Authors:  Mohammad Mahdi Forghanifard; Paniz Kasebi; Mohammad Reza Abbaszadegan
Journal:  Mol Cell Biochem       Date:  2020-10-24       Impact factor: 3.396

Review 9.  Gastric Cancer Stem Cells: A Glimpse on Metabolic Reprogramming.

Authors:  Martina Addeo; Giuseppina Di Paola; Henu Kumar Verma; Simona Laurino; Sabino Russi; Pietro Zoppoli; Geppino Falco; Pellegrino Mazzone
Journal:  Front Oncol       Date:  2021-06-16       Impact factor: 6.244

10.  Identification of Liver Cancer Stem Cell Stemness Markers Using a Comparative Analysis of Public Data Sets.

Authors:  Kirill Borziak; Joseph Finkelstein
Journal:  Stem Cells Cloning       Date:  2021-06-16
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