Literature DB >> 29275516

Report of the 12th Sphingolipid Club Meeting, Trabia, Italy (Sept. 7-10, 2017).

Thierry Levade1, Riccardo Ghidoni2.   

Abstract

We present here a report of the 12th Sphingolipid Club Meeting held in Trabia, Italy, on September 7-10, 2017. The meeting accounted for the presence of 120 young and senior scientists, coming from both European and overseas countries, interested in the sphingolipid field. The scientific program consisted in a total of 41 oral and 26 poster presentations. The participants contributed actively with formal discussions and informal exchange of views all along the meeting. The original results presented confirm the importance of sphingolipid in both physiological and pathological situations, and offer a promising platform to suggest innovative therapeutic strategies for different diseases.

Entities:  

Keywords:  Cancer; Enzymes; Neurodegeneration; Sphingolipids

Mesh:

Substances:

Year:  2017        PMID: 29275516     DOI: 10.1007/s00210-017-1452-6

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN: 0028-1298            Impact factor:   3.000


  14 in total

1.  Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells.

Authors:  Thomas Pinkert; David Furkert; Thomas Korte; Andreas Herrmann; Christoph Arenz
Journal:  Angew Chem Int Ed Engl       Date:  2017-02-03       Impact factor: 15.336

2.  Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction.

Authors:  Stephanie Schwalm; Sandra Beyer; Helena Frey; Riad Haceni; Georgios Grammatikos; Dominique Thomas; Gerd Geisslinger; Liliana Schaefer; Andrea Huwiler; Josef Pfeilschifter
Journal:  Am J Pathol       Date:  2017-08-12       Impact factor: 4.307

Review 3.  Sphingolipid metabolism in cancer signalling and therapy.

Authors:  Besim Ogretmen
Journal:  Nat Rev Cancer       Date:  2017-11-17       Impact factor: 60.716

Review 4.  Sphingolipids and their metabolism in physiology and disease.

Authors:  Yusuf A Hannun; Lina M Obeid
Journal:  Nat Rev Mol Cell Biol       Date:  2017-11-22       Impact factor: 94.444

5.  Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling.

Authors:  Franziska Peters; Susanne Vorhagen; Susanne Brodesser; Kristin Jakobshagen; Jens C Brüning; Carien M Niessen; Martin Krönke
Journal:  J Invest Dermatol       Date:  2015-02-23       Impact factor: 8.551

Review 6.  Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy.

Authors:  Jason Newton; Santiago Lima; Michael Maceyka; Sarah Spiegel
Journal:  Exp Cell Res       Date:  2015-03-11       Impact factor: 3.905

7.  Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsis.

Authors:  Nasr Y A Hemdan; Cynthia Weigel; Christina-Maria Reimann; Markus H Gräler
Journal:  Eur J Immunol       Date:  2016-10-20       Impact factor: 5.532

Review 8.  Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways.

Authors:  Carmen Garcia-Ruiz; Jose M Mato; Dennis Vance; Neil Kaplowitz; José C Fernández-Checa
Journal:  J Hepatol       Date:  2014-10-02       Impact factor: 25.083

9.  Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.

Authors:  Alba Di Pardo; Enrico Amico; Abdul Basit; Andrea Armirotti; Piyush Joshi; M Diana Neely; Romina Vuono; Salvatore Castaldo; Anna F Digilio; Francesco Scalabrì; Giuseppe Pepe; Francesca Elifani; Michele Madonna; Se Kyoo Jeong; Bu-Mahn Park; Maurizio D'Esposito; Aaron B Bowman; Roger A Barker; Vittorio Maglione
Journal:  Sci Rep       Date:  2017-07-13       Impact factor: 4.379

10.  SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.

Authors:  Daniel N Mitroi; Indulekha Karunakaran; Markus Gräler; Julie D Saba; Dan Ehninger; María Dolores Ledesma; Gerhild van Echten-Deckert
Journal:  Autophagy       Date:  2017-05-04       Impact factor: 16.016

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