| Literature DB >> 2927509 |
F Sprenger1, L M Stevens, C Nüsslein-Volhard.
Abstract
The maternal gene torso, required for determination of anterior and posterior terminal structures in the Drosophila embryo, was cloned using P-element tagging. Genetic evidence suggests that the action of the gene product is spatially restricted to the terminal regions; the torso messenger RNA, however, is evenly distributed. Structural similarities of the predicted torso protein with growth-factor receptor tyrosine kinases suggest that the spatial restriction of torso activity results from a localized activation of the torso protein at the anterior and posterior egg pole.Entities:
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Year: 1989 PMID: 2927509 DOI: 10.1038/338478a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962