Julia Smith1, Amanda S Bruce2, Morgan Glusman1, Joanie Thelen1, Sharon Lynch3, Jared M Bruce4. 1. University of Missouri-Kansas City, Department of Psychology, Kansas City, MO, United States. 2. Children's Mercy Hospital, Center for Healthy Lifestyles and Nutrition, Kansas City, MO, United States; University of Kansas Medical Center, Department of Pediatrics, Kansas City, KS, United States. 3. University of Kansas Medical Center, Department of Neurology, Kansas City, KS, United States. 4. University of Missouri-Kansas City, Department of Psychology, Kansas City, MO, United States; University of Missouri - Kansas City, Department of Biomedical and Health Informatics, Kansas City, MO, United States.
Abstract
BACKGROUND: Fatigue is prevalent in Multiple Sclerosis (MS), but little research indicates how to best quantify changes in fatigue over time. OBJECTIVE: Evaluate reliable change on the abbreviated Modified Fatigue Impact Scale (MFIS-5) in MS patients. METHODS: One-hundred sixty eight MS patients completed the MFIS-5 at baseline and follow-up as part of two larger studies. Test-retest reliability scores and reliable change indices were calculated. RESULTS: Differences of 4, 5, 6, and 7 points on the MFIS-5 represent statistically meaningful change at the .70, .80, .90, and .95 confidence intervals, respectively. CONCLUSIONS: The MFIS-5 can be used to quickly and reliably assess statistically meaningful changes in fatigue among MS patients.
BACKGROUND:Fatigue is prevalent in Multiple Sclerosis (MS), but little research indicates how to best quantify changes in fatigue over time. OBJECTIVE: Evaluate reliable change on the abbreviated Modified Fatigue Impact Scale (MFIS-5) in MSpatients. METHODS: One-hundred sixty eight MSpatients completed the MFIS-5 at baseline and follow-up as part of two larger studies. Test-retest reliability scores and reliable change indices were calculated. RESULTS: Differences of 4, 5, 6, and 7 points on the MFIS-5 represent statistically meaningful change at the .70, .80, .90, and .95 confidence intervals, respectively. CONCLUSIONS: The MFIS-5 can be used to quickly and reliably assess statistically meaningful changes in fatigue among MSpatients.
Authors: Virginia Meca-Lallana; María Brañas-Pampillón; Yolanda Higueras; Antonio Candeliere-Merlicco; Yolanda Aladro-Benito; Ofir Rodríguez-De la Fuente; Elisa Salas-Alonso; Jorge Maurino; Javier Ballesteros Journal: Mult Scler J Exp Transl Clin Date: 2019-11-09