Literature DB >> 2927397

Specific binding of estrogen receptor to the estrogen response element.

L Klein-Hitpass1, S Y Tsai, G L Greene, J H Clark, M J Tsai, B W O'Malley.   

Abstract

Gene transfer studies have shown that estrogen regulation of specific genes is mediated by estrogen response elements (ERE). We report that binding of the estrogen receptor to the ERE can be detected by a gel retardation (band shift) assay. This binding interaction was highly sequence and receptor specific. Methylation interference analysis showed that the ERE contact sites of estrogen receptor displayed a perfect twofold rotational symmetry. This is compatible with estrogen receptor binding to the ERE as a head-to-head dimer.

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Year:  1989        PMID： 2927397      PMCID： PMC362143          DOI： 10.1128/mcb.9.1.43-49.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  41 in total

1.  Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein.

Authors:  L Keegan; G Gill; M Ptashne
Journal:  Science       Date:  1986-02-14       Impact factor: 47.728

2.  Molecular model of the interaction between the glucocorticoid receptor and the regulatory elements of inducible genes.

Authors:  C Scheidereit; H M Westphal; C Carlson; H Bosshard; M Beato
Journal:  DNA       Date:  1986-10

3.  Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.

Authors:  K A Jones; K R Yamamoto; R Tjian
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

4.  Preparation of monoclonal antibodies to the avian progesterone receptor.

Authors:  W P Sullivan; T G Beito; J Proper; C J Krco; D O Toft
Journal:  Endocrinology       Date:  1986-10       Impact factor: 4.736

5.  An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells.

Authors:  L Klein-Hitpass; M Schorpp; U Wagner; G U Ryffel
Journal:  Cell       Date:  1986-09-26       Impact factor: 41.582

6.  Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line.

Authors:  A Seiler-Tuyns; P Walker; E Martinez; A M Mérillat; F Givel; W Wahli
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

Review 7.  Steroid receptor regulated transcription of specific genes and gene networks.

Authors:  K R Yamamoto
Journal:  Annu Rev Genet       Date:  1985       Impact factor: 16.830

8.  Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

Authors:  H Ponta; N Kennedy; P Skroch; N E Hynes; B Groner
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

9.  Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast.

Authors:  I A Hope; K Struhl
Journal:  Cell       Date:  1986-09-12       Impact factor: 41.582

10.  Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

Authors:  J Miller; A D McLachlan; A Klug
Journal:  EMBO J       Date:  1985-06       Impact factor: 11.598
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  41 in total

1.  Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers.

Authors:  T A Pham; J F Elliston; Z Nawaz; D P McDonnell; M J Tsai; B W O'Malley
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-15       Impact factor: 11.205

2.  Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells.

Authors:  L Klein-Hitpass; A C Cato; D Henderson; G U Ryffel
Journal:  Nucleic Acids Res       Date:  1991-03-25       Impact factor: 16.971

3.  Functional interaction of hybrid response elements with wild-type and mutant steroid hormone receptors.

Authors:  M Truss; G Chalepakis; E P Slater; S Mader; M Beato
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272

4.  Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending.

Authors:  A M Nardulli; D J Shapiro
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

5.  Proteolytic activity of the purified hormone-binding subunit in the estrogen receptor.

Authors:  A M Molinari; C Abbondanza; I Armetta; N Medici; S Minucci; B Moncharmont; V Nigro; G A Puca
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

6.  Characterisation of a genomic clone covering the structural mouse MyoD1 gene and its promoter region.

Authors:  J M Zingg; G P Alva; J P Jost
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

7.  Liver specific transcription factors of the HNF3-, C/EBP- and LFB1-families interact with the A-activator binding site.

Authors:  T Drewes; L Klein-Hitpass; G U Ryffel
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

8.  The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element.

Authors:  J Behrens; O Löwrick; L Klein-Hitpass; W Birchmeier
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

9.  Classification of breast cancer cells on the basis of a functional assay for estrogen receptor.

Authors:  D K Biswas; L Averboukh; S Sheng; K Martin; D S Ewaniuk; T F Jawde; F Wang; A B Pardee
Journal:  Mol Med       Date:  1998-07       Impact factor: 6.354

10.  Estrogen regulates the expression of several different estrogen receptor mRNA isoforms in rat pituitary.

Authors:  K E Friend; L W Ang; M A Shupnik
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205
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