| Literature DB >> 29273101 |
Jessica Cervantes1, Joaquin J Jimenez2, Gina M DelCanto3, Antonella Tosti4.
Abstract
Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.Entities:
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Year: 2018 PMID： 29273101 DOI： 10.1016/j.jisp.2017.10.013
Source DB: PubMed Journal: J Investig Dermatol Symp Proc ISSN： 1087-0024