Literature DB >> 2927251

Comparative study of cathinone and amphetamine on brown adipose thermogenesis.

M Tariq1, M W Islam, I A al-Meshal, F S el-Feraly, A M Ageel.   

Abstract

The effect of cathinone and amphetamine on brown adipose tissue thermogenesis and its modification with propranolol and timolol has been studied in rats. Both cathinone and amphetamine produced significant dose dependent increases in intracapsular brown adipose tissue (IBAT) and rectal temperatures. Amphetamine was found to be three times more potent as compared to cathinone, on a dose basis. Pretreatment of animals with propranolol and timolol individually inhibited cathinone and amphetamine induced hyperthermia. These findings suggest the involvement of beta adrenergic receptors in cathinone and amphetamine induced thermogenesis.

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Year:  1989        PMID： 2927251     DOI： 10.1016/0024-3205(89)90494-3

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  8 in total

Review 1.  Pharmacological approaches for the treatment of obesity.

Authors:  José-Antonio Fernández-López; Xavier Remesar; Màrius Foz; Marià Alemany
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 2.  The preclinical pharmacology of mephedrone; not just MDMA by another name.

Authors:  A R Green; M V King; S E Shortall; K C F Fone
Journal:  Br J Pharmacol       Date:  2014-05       Impact factor: 8.739

Review 3.  Khat use and appetite: an overview and comparison of amphetamine, khat and cathinone.

Authors:  Andrine M Lemieux; Bingshuo Li; Mustafa al'Absi
Journal:  J Ethnopharmacol       Date:  2014-11-28       Impact factor: 4.360

Review 4.  Caffeine provokes adverse interactions with 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and related psychostimulants: mechanisms and mediators.

Authors:  N Vanattou-Saïfoudine; R McNamara; A Harkin
Journal:  Br J Pharmacol       Date:  2012-11       Impact factor: 8.739

5.  Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia.

Authors:  S E Shortall; A R Green; K M Swift; K C F Fone; M V King
Journal:  Br J Pharmacol       Date:  2013-02       Impact factor: 8.739

6.  Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone).

Authors:  M L Miller; K M Creehan; D Angrish; D J Barlow; K L Houseknecht; T J Dickerson; M A Taffe
Journal:  Drug Alcohol Depend       Date:  2012-07-23       Impact factor: 4.492

7.  The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature.

Authors:  Khadija M Alawi; Aisah A Aubdool; Lihuan Liang; Elena Wilde; Abhinav Vepa; Maria-Paraskevi Psefteli; Susan D Brain; Julie E Keeble
Journal:  FASEB J       Date:  2015-07-01       Impact factor: 5.191

8.  Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats.

Authors:  M Jerry Wright; Deepshikha Angrish; Shawn M Aarde; Deborah J Barlow; Matthew W Buczynski; Kevin M Creehan; Sophia A Vandewater; Loren H Parsons; Karen L Houseknecht; Tobin J Dickerson; Michael A Taffe
Journal:  PLoS One       Date:  2012-08-31       Impact factor: 3.240
  8 in total

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