Literature DB >> 29272341

Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System.

Troy Watson1, Jason Hickok1, Sarah Fraker1, Kimberly Korwek1, Russell E Poland1, Edward Septimus1.   

Abstract

In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difficile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. These findings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.

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Year:  2018        PMID： 29272341     DOI： 10.1093/cid/cix1112

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  2 in total

1.  Antibiotic Exposure and Risk for Hospital-Associated Clostridioides difficile Infection.

Authors:  Brandon J Webb; Aruna Subramanian; Bert Lopansri; Bruce Goodman; Peter Bjorn Jones; Jeffrey Ferraro; Edward Stenehjem; Samuel M Brown
Journal:  Antimicrob Agents Chemother       Date:  2020-03-24       Impact factor: 5.191

2.  SYN-007, an Orally Administered Beta-Lactamase Enzyme, Protects the Gut Microbiome from Oral Amoxicillin/Clavulanate without Adversely Affecting Antibiotic Systemic Absorption in Dogs.

Authors:  Sheila Connelly; Brian Fanelli; Nur A Hasan; Rita R Colwell; Michael Kaleko
Journal:  Microorganisms       Date:  2020-01-22
  2 in total

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