Literature DB >> 29271956

[Targeted Bifunctional Proteins and Hybrid Nanoconstructs for Cancer Diagnostics and Therapies].

S M Deyev1,2, E N Lebedenko1,3.   

Abstract

In this review, the authors' works published within the past 5 years devoted to the development of bifunctional hybrid nanostructures based on the targeting polypeptides and nanoparticles of various origin (quantum dots, nanogold, nanodiamonds, upconversion nanoparticles, magnetic and polymer nanoparticles) as modules that ensure visualization and various damaging effects on cancer cells are surveyed and the prospects of their application in theranostics and precision medicine have been contemplated.

Entities:  

Keywords:  Biocomputing; DARPins; HER2; NIR; exotoxin A; imaging; nanogold; photodynamic and photothermal therapies; protein photosensitizers; riboflavin; scFv; tumor xenografts; upconverting nanophosphores

Mesh:

Substances:

Year:  2017        PMID: 29271956     DOI: 10.7868/S0026898417060040

Source DB:  PubMed          Journal:  Mol Biol (Mosk)        ISSN: 0026-8984


  4 in total

1.  Radioactive (90Y) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer.

Authors:  Evgenii L Guryev; Natalia O Volodina; Natalia Y Shilyagina; Sergey V Gudkov; Irina V Balalaeva; Arthur B Volovetskiy; Alexander V Lyubeshkin; Alexey V Sen'; Sergey A Ermilov; Vladimir A Vodeneev; Rem V Petrov; Andrei V Zvyagin; Zhores I Alferov; Sergey M Deyev
Journal:  Proc Natl Acad Sci U S A       Date:  2018-09-07       Impact factor: 11.205

Review 2.  Neuroblastoma Origin and Therapeutic Targets for Immunotherapy.

Authors:  Irina V Kholodenko; Daniel V Kalinovsky; Igor I Doronin; Sergey M Deyev; Roman V Kholodenko
Journal:  J Immunol Res       Date:  2018-07-11       Impact factor: 4.818

Review 3.  Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy.

Authors:  Andrew J Gauger; Kian K Hershberger; Lyudmila M Bronstein
Journal:  Front Chem       Date:  2020-07-07       Impact factor: 5.221

4.  UCNP-based Photoluminescent Nanomedicines for Targeted Imaging and Theranostics of Cancer.

Authors:  Evgenii L Guryev; Anita S Smyshlyaeva; Natalia Y Shilyagina; Evgeniya A Sokolova; Samah Shanwar; Alexey B Kostyuk; Alexander V Lyubeshkin; Alexey A Schulga; Elena V Konovalova; Quan Lin; Indrajit Roy; Irina V Balalaeva; Sergey M Deyev; Andrei V Zvyagin
Journal:  Molecules       Date:  2020-09-19       Impact factor: 4.411

  4 in total

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