| Literature DB >> 29269194 |
H Mesrar1, J Mesrar2, B Maillier3, S Kraoua4, L Chapoutot3, B Delclaux4.
Abstract
Lemierre's syndrome is a rare and severe sepsis that can rapidly lead to a life-threatening condition in the absence of early management. This syndrome described at the beginning of the 20th century combines oropharyngeal infection complicated with septic thrombosis of the internal jugular vein and septic emboli predominantly pulmonary. Fusobacterium necrophorum, anaerobic germ, Gram negative bacillus is the main germ in this "necrobacillosis". The diagnosis is should be confirmed precociously with cervicothoracic CT-scan, reference exam, and bacteriological examinations (especially in atypical forms). Its management consists of an emergency antibiotic treatment, combining a third-generation cephalosporin or a betalactam with metronidazole, anticoagulant therapy to be reserved for high-risk situations related to thrombosis. Surgical treatment may be required.Entities:
Keywords: Abcès pulmonaires; Fusobacterium necrophorum; Infection oropharyngée; Jugular septic thrombosis; Lemierre's syndrome; Lung abscesses; Oropharyngeal infection; Syndrome de Lemierre; Thrombose septique jugulaire
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Year: 2017 PMID: 29269194 DOI: 10.1016/j.revmed.2017.11.005
Source DB: PubMed Journal: Rev Med Interne ISSN: 0248-8663 Impact factor: 0.728