Literature DB >> 29268334

Essential signaling in NF2 loss-related tumours: the therapeutic potential of CRL4DCAF1 and mTOR combined inhibition.

Helena J Janse van Rensburg1, Xiaolong Yang1.   

Abstract

Entities:  

Year:  2017        PMID: 29268334      PMCID: PMC5723899          DOI: 10.21037/jtd.2017.09.34

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


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  23 in total

1.  Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

Authors:  Wei Li; Liru You; Jonathan Cooper; Gaia Schiavon; Angela Pepe-Caprio; Lu Zhou; Ryohei Ishii; Marco Giovannini; C Oliver Hanemann; Stephen B Long; Hediye Erdjument-Bromage; Pengbo Zhou; Paul Tempst; Filippo G Giancotti
Journal:  Cell       Date:  2010-02-19       Impact factor: 41.582

2.  The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of Merlin.

Authors:  Kana T Furukawa; Kazunari Yamashita; Natsuki Sakurai; Shigeo Ohno
Journal:  Cell Rep       Date:  2017-08-08       Impact factor: 9.423

3.  Incidence of vestibular schwannoma and neurofibromatosis 2 in the North West of England over a 10-year period: higher incidence than previously thought.

Authors:  D Gareth R Evans; Anthony Moran; Andrew King; S Saeed; Nihal Gurusinghe; Richard Ramsden
Journal:  Otol Neurotol       Date:  2005-01       Impact factor: 2.311

4.  Compensative shuttling of merlin to phosphorylation on serine 518 in vestibular schwannoma.

Authors:  Jingrong Lü; Jing Zou; Hao Wu; Lihui Cai
Journal:  Laryngoscope       Date:  2008-01       Impact factor: 3.325

5.  Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas.

Authors:  M H Ruttledge; J Sarrazin; S Rangaratnam; C M Phelan; E Twist; P Merel; O Delattre; G Thomas; M Nordenskjöld; V P Collins
Journal:  Nat Genet       Date:  1994-02       Impact factor: 38.330

6.  Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.

Authors:  Miguel A López-Lago; Tomoyo Okada; Miguel M Murillo; Nick Socci; Filippo G Giancotti
Journal:  Mol Cell Biol       Date:  2009-05-18       Impact factor: 4.272

7.  An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.

Authors:  Teresa A Soucy; Peter G Smith; Michael A Milhollen; Allison J Berger; James M Gavin; Sharmila Adhikari; James E Brownell; Kristine E Burke; David P Cardin; Stephen Critchley; Courtney A Cullis; Amanda Doucette; James J Garnsey; Jeffrey L Gaulin; Rachel E Gershman; Anna R Lublinsky; Alice McDonald; Hirotake Mizutani; Usha Narayanan; Edward J Olhava; Stephane Peluso; Mansoureh Rezaei; Michael D Sintchak; Tina Talreja; Michael P Thomas; Tary Traore; Stepan Vyskocil; Gabriel S Weatherhead; Jie Yu; Julie Zhang; Lawrence R Dick; Christopher F Claiborne; Mark Rolfe; Joseph B Bolen; Steven P Langston
Journal:  Nature       Date:  2009-04-09       Impact factor: 49.962

8.  The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.

Authors:  Nailing Zhang; Haibo Bai; Karen K David; Jixin Dong; Yonggang Zheng; Jing Cai; Marco Giovannini; Pentao Liu; Robert A Anders; Duojia Pan
Journal:  Dev Cell       Date:  2010-07-20       Impact factor: 12.270

Review 9.  Role of Merlin/NF2 inactivation in tumor biology.

Authors:  A M Petrilli; C Fernández-Valle
Journal:  Oncogene       Date:  2015-04-20       Impact factor: 9.867

10.  Mutations in UBA3 confer resistance to the NEDD8-activating enzyme inhibitor MLN4924 in human leukemic cells.

Authors:  G Wei Xu; Julia I Toth; Sara R da Silva; Stacey-Lynn Paiva; Julie L Lukkarila; Rose Hurren; Neil Maclean; Mahadeo A Sukhai; Rabindra N Bhattacharjee; Carolyn A Goard; Bruno Medeiros; Patrick T Gunning; Sirano Dhe-Paganon; Matthew D Petroski; Aaron D Schimmer
Journal:  PLoS One       Date:  2014-04-01       Impact factor: 3.240

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  1 in total

Review 1.  mTOR Signaling and Potential Therapeutic Targeting in Meningioma.

Authors:  Benjamin Pinker; Anna-Maria Barciszewska
Journal:  Int J Mol Sci       Date:  2022-02-10       Impact factor: 5.923

  1 in total

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