| Literature DB >> 29264436 |
Giovanni Battista Levi Sandri1, Giuseppe Maria Ettorre1, Valerio Giannelli2, Marco Colasanti1, Rosa Sciuto3, Giuseppe Pizzi4, Roberto Cianni5, Gianpiero D'Offizi6, Mario Antonini7, Giovanni Vennarecci1, Pierleone Lucatelli8.
Abstract
Liver transplantation (LT) for hepatocellular carcinoma (HCC) within the Milan criteria (MC) is nowadays a curative procedure. Yttrium-90 microspheres radioembolization (Y90-RE) has shown to be an effective and safe treatment of primary liver tumors. The aim of this work is to offer a view on the publications which report on the use of Y90-RE as bridge or downstaging prior to LT. Twenty articles have been considered for this world review. About 178 LT in patients were treated with Y90-RE prior to LT. Most of patients had a downstaging strategy. In all series alpha-fetoproteins decreased between Y90-RE and LT. Therefore, Y90-RE may have an important role in the bridge and downstaging treatments.Entities:
Keywords: Yttrium; bridging; downstaging; hepatocellular carcinoma (HCC); liver transplantation (LT); radioembolization
Year: 2017 PMID: 29264436 PMCID: PMC5723750 DOI: 10.21037/tgh.2017.11.11
Source DB: PubMed Journal: Transl Gastroenterol Hepatol ISSN: 2415-1289