Literature DB >> 2926419

Ischaemic brain damage is still common in fatal non-missile head injury.

D I Graham1, I Ford, J H Adams, D Doyle, G M Teasdale, A E Lawrence, D R McLellan.   

Abstract

A detailed neuropathological examination has been undertaken on a consecutive series of head injuries dying in the Institute of Neurological Sciences, Glasgow, between 1968-72 (151 cases) and 1981-82 (112 cases) in order to determine the frequency and distribution of any ischaemic brain damage. Ischaemic damage was found in the brains of 92% of the 1968-72 cases and in 88% of the 1981-82 cases: there was no statistical difference in the amount of moderately severe and severe ischaemic damage in the two groups, 55% and 54% respectively. There was evidence, however, that an increased number of patients with severe ischaemic brain damage was admitted in 1981-82 as a result of a changed admission policy of the Department of Neurosurgery that resulted in an increased detection of intracranial haematomas. It is concluded that ischaemic brain damage is still common after severe head injury, and it seems likely that it remains an important cause of mortality and morbidity.

Entities:  

Mesh:

Year:  1989        PMID: 2926419      PMCID: PMC1032409          DOI: 10.1136/jnnp.52.3.346

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  14 in total

1.  The outcome from severe head injury with early diagnosis and intensive management.

Authors:  D P Becker; J D Miller; J D Ward; R P Greenberg; H F Young; R Sakalas
Journal:  J Neurosurg       Date:  1977-10       Impact factor: 5.115

2.  Hazards of inter-hospital transfer of comatose head-injured patients.

Authors:  D Gentleman; B Jennett
Journal:  Lancet       Date:  1981-10-17       Impact factor: 79.321

3.  Brain damage in fatal non-missile head injury without high intracranial pressure.

Authors:  D I Graham; A E Lawrence; J H Adams; D Doyle; D R McLellan
Journal:  J Clin Pathol       Date:  1988-01       Impact factor: 3.411

4.  Neurosurgical resources and transfer policies for head injuries.

Authors:  J S Bryden; B Jennett
Journal:  Br Med J (Clin Res Ed)       Date:  1983-06-04

5.  Extradural hematoma: toward zero mortality. A prospective study.

Authors:  A P Bricolo; L M Pasut
Journal:  Neurosurgery       Date:  1984-01       Impact factor: 4.654

6.  Outcome in 200 consecutive cases of severe head injury treated in San Diego County: a prospective analysis.

Authors:  S A Bowers; L F Marshall
Journal:  Neurosurgery       Date:  1980-03       Impact factor: 4.654

7.  Secondary insults to the injured brain.

Authors:  J D Miller; D P Becker
Journal:  J R Coll Surg Edinb       Date:  1982-09

8.  Patients with head injury who talk and die.

Authors:  P L Reilly; D I Graham; J H Adams; B Jennett
Journal:  Lancet       Date:  1975-08-30       Impact factor: 79.321

9.  Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases.

Authors:  J H Adams; D I Graham; L S Murray; G Scott
Journal:  Ann Neurol       Date:  1982-12       Impact factor: 10.422

10.  Ischaemic brain damage in fatal non-missile head injuries.

Authors:  D I Graham; J H Adams; D Doyle
Journal:  J Neurol Sci       Date:  1978-12       Impact factor: 3.181

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  61 in total

1.  The neuropathology of the vegetative state after head injury.

Authors:  J H Adams; B Jennett; D R McLellan; L S Murray; D I Graham
Journal:  J Clin Pathol       Date:  1999-11       Impact factor: 3.411

2.  Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial.

Authors:  Eileen M Bulger; Susanne May; Karen J Brasel; Martin Schreiber; Jeffrey D Kerby; Samuel A Tisherman; Craig Newgard; Arthur Slutsky; Raul Coimbra; Scott Emerson; Joseph P Minei; Berit Bardarson; Peter Kudenchuk; Andrew Baker; Jim Christenson; Ahamed Idris; Daniel Davis; Timothy C Fabian; Tom P Aufderheide; Clifton Callaway; Carolyn Williams; Jane Banek; Christian Vaillancourt; Rardi van Heest; George Sopko; J Steven Hata; David B Hoyt
Journal:  JAMA       Date:  2010-10-06       Impact factor: 56.272

3.  A clinical decision rule to predict adult patients with traumatic intracranial haemorrhage who do not require intensive care unit admission.

Authors:  Daniel K Nishijima; Kiarash Shahlaie; Angela Echeverri; James F Holmes
Journal:  Injury       Date:  2011-08-11       Impact factor: 2.586

4.  Hippocampal pathology in fatal non-missile human head injury.

Authors:  M J Kotapka; D I Graham; J H Adams; T A Gennarelli
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

5.  Red Blood Cell Transfusion and Transfusion Alternatives in Traumatic Brain Injury.

Authors:  Andreas H Kramer; Peter Le Roux
Journal:  Curr Treat Options Neurol       Date:  2012-02-08       Impact factor: 3.598

6.  Physiological and histopathological responses following closed rotational head injury depend on direction of head motion.

Authors:  Stephanie A Eucker; Colin Smith; Jill Ralston; Stuart H Friess; Susan S Margulies
Journal:  Exp Neurol       Date:  2010-09-25       Impact factor: 5.330

7.  Intracranial pressure and cerebral oxygenation changes after decompressive craniectomy in a child with traumatic brain swelling.

Authors:  A A Figaji; A G Fieggen; S J I Sandler; A C Argent; P D Le Roux; J C Peter
Journal:  Childs Nerv Syst       Date:  2007-07-14       Impact factor: 1.475

8.  Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.

Authors:  Paul Vespa; Marvin Bergsneider; Nayoa Hattori; Hsiao-Ming Wu; Sung-Cheng Huang; Neil A Martin; Thomas C Glenn; David L McArthur; David A Hovda
Journal:  J Cereb Blood Flow Metab       Date:  2005-06       Impact factor: 6.200

Review 9.  Practical aspects of bedside cerebral hemodynamics monitoring in pediatric TBI.

Authors:  Anthony A Figaji
Journal:  Childs Nerv Syst       Date:  2010-04       Impact factor: 1.475

10.  Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans.

Authors:  Kunihiro Uryu; Xiao-Han Chen; Dan Martinez; Kevin D Browne; Victoria E Johnson; David I Graham; Virginia M-Y Lee; John Q Trojanowski; Douglas H Smith
Journal:  Exp Neurol       Date:  2007-07-10       Impact factor: 5.330

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