Literature DB >> 29263741

Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease.

Jérémy Flais1,2, Guillaume Coiffier1,2, Eric Brillet3, Aleth Perdriger1,2, Pascal Guggenbuhl1,4,2.   

Abstract

A 55-year-old man was hospitalized for a low back pain lasting for 3 months. Spinal MRI revealed a suggestive aspect of multilevel discitis L5-S1-S2 with paravertebral abscess. A thoraco-abdominal CT scan confirmed the presence of multiple pathological lymph nodes in several locations, bilateral micronodular pulmonary infiltrate; it also showed mirror bone erosions of vertebral L5 and S1 endplates, suggestive of disseminated tuberculosis with lung involvement and lymphadenopathy. A discovertebral L5-S1 biopsy was performed confirming the diagnosis of metastatic prostatic adenocarcinoma including a tumor infiltration of the intervertebral disc, without arguments for a septic processus superimposed without tuberculosis granuloma. Although rare, cases of metastases located at the disco-vertebral junction including prostatic cancer have already been described, and should be known to the clinician. The differential diagnosis with an infectious spondylodiscitis can be difficult in some case around the vertebral disc and in case of epiduritis and soft tissues involvement on MRI sequences. Disco-vertebral biopsy remains the cornerstone of the diagnosis.

Entities:  

Keywords:  metastasis; prostate cancer; spondylodiscitis; tuberculosis

Year:  2017        PMID: 29263741      PMCID: PMC5726217          DOI: 10.11138/ccmbm/2017.14.1.239

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  4 in total

Review 1.  Imaging of musculoskeletal tuberculosis: a new look at an old disease.

Authors:  James F Griffith; Shekhar M Kumta; Ping Chung Leung; Jack C Y Cheng; Louis T C Chow; Constantine Metreweli
Journal:  Clin Orthop Relat Res       Date:  2002-05       Impact factor: 4.176

2.  Problems in distinguishing spinal tuberculosis from neoplasia on MRI.

Authors:  R K Gupta; P Agarwal; H Rastogi; S Kumar; R V Phadke; N Krishnani
Journal:  Neuroradiology       Date:  1996-05       Impact factor: 2.804

3.  Metastatic disease involving the discovertebral junction of the spine.

Authors:  Yousuke Kakitsubata; Daphne J Theodorou; Stavroula J Theodorou; Kazuki Nabeshima; Shozo Tamura
Journal:  Joint Bone Spine       Date:  2008-11-01       Impact factor: 4.929

4.  Intervertebral disc abnormalities associated with vertebral metastasis: observations in patients and cadavers with prostatic cancer.

Authors:  D Resnick; G Niwayama
Journal:  Invest Radiol       Date:  1978 May-Jun       Impact factor: 6.016

  4 in total
  5 in total

1.  [CT spectral curve in differentiating spinal tumor metastasis and infections].

Authors:  Y Yuan; N Lang; H S Yuan
Journal:  Beijing Da Xue Xue Bao Yi Xue Ban       Date:  2020-10-19

2.  Rapid-kilovoltage-switching dual-energy computed tomography (CT) for differentiating spinal osteolytic metastases from spinal infections.

Authors:  Yuan Yuan; Ning Lang; Huishu Yuan
Journal:  Quant Imaging Med Surg       Date:  2021-02

3.  Development and Validation of a Scoring System for Differential Diagnosis of Tuberculosis and Metastatic Tumor in the Spine.

Authors:  Shuang Cao; Xin Gao; Guangjian Bai; Baoquan Xin; Tao Wang; Jiashi Cao; Kai Lv; Chengzhang Zhu; Xiangzhi Ni; Weiwei Zou; Yejin Zhou; Jianru Xiao; Tielong Liu
Journal:  Infect Drug Resist       Date:  2021-02-04       Impact factor: 4.003

4.  Rare Presentation of Mycobacterium tuberculosis Mimicking Prostate Cancer.

Authors:  Seyed Mohammad Nahidi; Harman Singh; Sharang Tickoo; Leonidha Duka; Jung Won; Jennifer Gulas
Journal:  J Med Cases       Date:  2022-02-16

5.  A Scoring System for Outpatient Orthopedist to Preliminarily Distinguish Spinal Metastasis from Spinal Tuberculosis: A Retrospective Analysis of 141 Patients.

Authors:  Xing Du; Yuxiao She; Yunsheng Ou; Yong Zhu; Wei Luo; Dianming Jiang
Journal:  Dis Markers       Date:  2021-05-29       Impact factor: 3.434

  5 in total

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