| Literature DB >> 29262340 |
Nicole Glodde1, Michael Hölzel2.
Abstract
Mutant RAS is a major oncoprotein in human cancer and PD-L1 is a key driver of cancer immune evasion. In this issue of Immunity, Coelho et al. (2017) demonstrate that oncogenic RAS signaling promotes tumor immune escape by stabilizing PD-L1 mRNA.Entities:
Mesh:
Substances:
Year: 2017 PMID: 29262340 DOI: 10.1016/j.immuni.2017.12.001
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745