Literature DB >> 29256248

Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol.

Ren-Jin Tang1, Thierry Milcent1, Benoit Crousse1.   

Abstract

Regioselective halogenation of arenes and heterocycles with N-halosuccinimides in fluorinated alcohols is disclosed. Under mild condition reactions, a wide diversity of halogenated arenes are obtained in good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of one-pot sequential halogenation and halogenation-Suzuki cross-coupling reactions.

Entities:  

Year:  2018        PMID： 29256248     DOI： 10.1021/acs.joc.7b02920

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  13 in total

Review 1.  Halogenation in Fungi: What Do We Know and What Remains to Be Discovered?

Authors:  Bastien Cochereau; Laurence Meslet-Cladière; Yves François Pouchus; Olivier Grovel; Catherine Roullier
Journal:  Molecules       Date:  2022-05-14       Impact factor: 4.927

2.  "CinNapht" dyes: a new cinnoline/naphthalimide fused hybrid fluorophore. Synthesis, photo-physical study and use for bio-imaging.

Authors:  Minh-Duc Hoang; Jean-Baptiste Bodin; Farah Savina; Vincent Steinmetz; Jérôme Bignon; Philippe Durand; Gilles Clavier; Rachel Méallet-Renault; Arnaud Chevalier
Journal:  RSC Adv       Date:  2021-09-08       Impact factor: 4.036

3.  Friedel-Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents.

Authors:  Ren-Jin Tang; Thierry Milcent; Benoit Crousse
Journal:  RSC Adv       Date:  2018-03-13       Impact factor: 4.036

4.  Site-Selective C-H alkylation of Complex Arenes by a Two-Step Aryl Thianthrenation-Reductive Alkylation Sequence.

Authors:  Beatrice Lansbergen; Paola Granatino; Tobias Ritter
Journal:  J Am Chem Soc       Date:  2021-05-24       Impact factor: 15.419

5.  Late-Stage Amination of Drug-Like Benzoic Acids: Access to Anilines and Drug Conjugates through Directed Iridium-Catalyzed C-H Activation.

Authors:  Erik Weis; Magnus J Johansson; Belén Martín-Matute
Journal:  Chemistry       Date:  2021-11-17       Impact factor: 5.020

6.  Site-Selective C-H Functionalization-Sulfination Sequence to Access Aryl Sulfonamides.

Authors:  Eva Maria Alvarez; Matthew B Plutschack; Florian Berger; Tobias Ritter
Journal:  Org Lett       Date:  2020-04-07       Impact factor: 6.005

7.  Suzuki-Type Cross-Coupling Reaction of Unprotected 3-Iodoindazoles with Pinacol Vinyl Boronate: An Expeditive C-3 Vinylation of Indazoles under Microwave Irradiation.

Authors:  Gonzalo Vera; Benjamín Diethelm; Claudio A Terraza; Gonzalo Recabarren-Gajardo
Journal:  Molecules       Date:  2018-08-16       Impact factor: 4.411

8.  Organic Dye-Catalyzed, Visible-Light Photoredox Bromination of Arenes and Heteroarenes Using N-Bromosuccinimide.

Authors:  David A Rogers; Roxanne G Brown; Zachary C Brandeburg; Eric Y Ko; Megan D Hopkins; Gabriel LeBlanc; Angus A Lamar
Journal:  ACS Omega       Date:  2018-10-09

9.  DABCO as a practical catalyst for aromatic halogenation with N-halosuccinimides.

Authors:  Haiyan Xu; Lanping Hu; Guanghua Zhu; Yueping Zhu; Yang Wang; Zheng-Guang Wu; You Zi; Weichun Huang
Journal:  RSC Adv       Date:  2022-03-02       Impact factor: 3.361

10.  Site-Selective C-H Oxygenation via Aryl Sulfonium Salts.

Authors:  Ruocheng Sang; Stamatis E Korkis; Wanqi Su; Fei Ye; Pascal S Engl; Florian Berger; Tobias Ritter
Journal:  Angew Chem Int Ed Engl       Date:  2019-09-24       Impact factor: 15.336
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.