Fast Quantitation of Pyrazole Fungicides in Wine by Ambient Ionization Mass Spectrometry.

Fungicides are widely used for growing the grapes that are used for making wines. Chromatography coupled with tandem mass spectrometry is usually time and labor consuming for quantitation of fungicides in wines. In this work, a simple ambient mass spectrometry method using paper capillary spray was developed for the fast quantitation of four pyrazole fungicides in wines. Direct analysis of the wine samples was achieved without any sample preparation, obtaining limits of quantitation as low as 2 ng/mL for all four pyrazole fungicides. Quality control experiments also showed adequate accuracy and precision for the analysis of pyrazole fungicides in wine products.